ArticleFrontiers in neuroscience2011
Sensing via intestinal sweet taste pathways.
Article in Frontiers in neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Pooled it
- Influence of sucrose ingestion on brainstem and hypothalamic intrinsic oscillations in lean and obese women.Gastroenterology · 2014Trial
- Disordered control of intestinal sweet taste receptor expression and glucose absorption in type 2 diabetes.Diabetes · 2013Trial
- Emerging Role of Taste Receptors, Entero-Endocrine Cells in Type 2 Diabetes and Metabolic Disorders.Nutrients · 2026Review
- Dipeptidyl-peptidase 4 (DPP4) mediates fatty acid uptake inhibition by glucose via TAS1R3 and GLUT-2 in Caco-2 enterocytes.Heliyon · 2024Article
- Nutritive/non-nutritive sweeteners and high fat diet contribute to dysregulation of sweet taste receptors and metabolic derangements in oral, intestinal and central nervous tissues.European journal of nutrition · 2023Article
- Exploring the potential for an evolutionarily conserved role of the taste 1 receptor gene family in gut sensing mechanisms of fish.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Article
- The complex involvement of the digestive tract in human defense behavior - structural and functional arguments.Journal of medicine and life · 2022Review
- An alternative pathway for sweet sensation: possible mechanisms and physiological relevance.Pflugers Archiv : European journal of physiology · 2020Review
- Stomach 'tastes' the food and adjusts its emptying: A neurophysiological hypothesis (Review).Experimental and therapeutic medicine · 2020Review
- Fasting glucagon-like peptide 1 concentration is associated with lower carbohydrate intake and increases with overeating.Journal of endocrinological investigation · 2019Article
- Sweet taste receptor inhibitors: Potential treatment for equine insulin dysregulation.PloS one · 2018Article
- Effect of chyme viscosity and nutrient feedback mechanism on gastric emptying.Chemical engineering science · 2017Article
- Sugars, Sweet Taste Receptors, and Brain Responses.Nutrients · 2017Review
- The flavanone homoeriodictyol increases SGLT-1-mediated glucose uptake but decreases serotonin release in differentiated Caco-2 cells.PloS one · 2017Article
- Ghrelin, CCK, GLP-1, and PYY(3-36): Secretory Controls and Physiological Roles in Eating and Glycemia in Health, Obesity, and After RYGB.Physiological reviews · 2017Review
- A High-Throughput Automated Microfluidic Platform for Calcium Imaging of Taste Sensing.Molecules (Basel, Switzerland) · 2016Article
- Catecholamines Facilitate Fuel Expenditure and Protect Against Obesity via a Novel Network of the Gut-Brain Axis in Transcription Factor Skn-1-deficient Mice.EBioMedicine · 2016Article
- Molecules implicated in glucose homeostasis are differentially expressed in the trachea of lean and obese Zucker rats.European journal of histochemistry : EJH · 2016Article
- The aglycone of ginsenoside Rg3 enables glucagon-like peptide-1 secretion in enteroendocrine cells and alleviates hyperglycemia in type 2 diabetic mice.Scientific reports · 2015Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The detection of nutrients in the gastrointestinal (GI) tract is of fundamental significance to the control of motility, glycemia and energy intake, and yet we barely know the most fundamental aspects of this process. This is in stark contrast to the mechanisms underlying the detection of lingual taste, which have been increasingly well characterized in recent years, and which provide an excellent starting point for characterizing nutrient detection in the intestine. This review focuses on the form and function of sweet taste transduction mechanisms identified in the intestinal tract; it does not focus on sensors for fatty acids or proteins. It examines the intestinal cell types equipped with sweet taste transduction molecules in animals and humans, their location, and potential signals that transduce the presence of nutrients to neural pathways involved in reflex control of GI motility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.