Evidence map›Paper›PMID 21519343›Full record

ArticleLeukemia2011

DNMT3A mutational analysis in primary myelofibrosis, chronic myelomonocytic leukemia and advanced phases of myeloproliferative neoplasms.

O Abdel-Wahab, A Pardanani, R Rampal, T L Lasho, R L Levine, A Tefferi

Abstract readLetter
In one paragraph

Article in Leukemia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it, 147 citations in OpenAlex.

  1. [Effects of DNMT3A gene mutations on prognosis of patients with acute myeloid leukemia: a meta-analysis].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2015
    Pooled it
  2. Trial
  3. Trial
  4. The Role and Impact of Non-driver Gene Mutations in Myelofibrosis.Current hematologic malignancy reports · 2026
    Review
  5. Epigenetic alterations in Myeloid Malignancies.Advances in experimental medicine and biology · 2026
    Review
  6. Review
  7. CD7-positive leukemic blasts withFrontiers in oncology · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. The Molecular Genetics of Myeloproliferative Neoplasms.Cold Spring Harbor perspectives in medicine · 2020
    Review
  18. Article
  19. Nuclear-Cytoplasmic Transport Is a Therapeutic Target in Myelofibrosis.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

O Abdel-Wahab
A Pardanani
R Rampal
T L Lasho
R L Levine
A Tefferi
Mayo Clinic in Arizona · USMemorial Sloan Kettering Cancer Center · US

Funding

Molecular Pathogenesis and Therapy of ET and PMFR01CA151949 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI LEVINE, ROSS L · 2010 to 2016
$2.3M
NCI NIH HHS R01 CA151949
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedCohort StudiesDisease ProgressionDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNA Mutational AnalysisFemaleHeterozygoteHumansLeukemia, Myelomonocytic, ChronicMaleMiddle AgedMyeloproliferative DisordersNeoplasm ProteinsPrimary MyelofibrosisPrognosisDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT3A protein, humanNeoplasm Proteins

Identifiers

PMID21519343
PMCPMC4640464
OpenAlexW2117206679

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.