Evidence map›Paper›PMID 21518829›Full record

ReviewThe Journal of general physiology2011

Origins of ion selectivity in potassium channels from the perspective of channel block.

Crina M Nimigean, Toby W Allen

Abstract readReview
In one paragraph

Review in The Journal of general physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
  2. High-Throughput MicroED for Probing Ion Channel Dynamics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Conductance selectivity of NaProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Structural properties determining low KThe Journal of biological chemistry · 2018
    Article
  13. Review
  14. Article
  15. Ion channels and ion selectivity.Essays in biochemistry · 2017
    Review
  16. Modeling the human NaDrug design, development and therapy · 2017
    Article
  17. Pore size matters for potassium channel conductance.The Journal of general physiology · 2016
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Crina M NimigeanDepartment of Anesthesiology, Weill Medical College, Cornell University, New York, NY 10065, USA. crn2002@­med.cornell.edu
Toby W Allen

Funding

Molecular Mechanisms of Potassium Channel Permeation and GatingR01GM088352 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI NIMIGEAN, CRINA M · 2010 to 2025
$5.6M
MECHANISM OF ION CHANNEL MODULATION BY LIGANDSR01GM077560 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI NIMIGEAN, CRINA M · 2007 to 2011
$1.9M
NIGMS NIH HHS GM077560NIGMS NIH HHS R01 GM077560NIGMS NIH HHS R01 GM088352
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Ion Channel GatingModels, MolecularPotassiumPotassium Channel BlockersPotassium ChannelsProtein Structure, TertiarySodiumSubstrate SpecificityPotassiumPotassium Channel BlockersPotassium ChannelsSodium

Identifiers

PMID21518829
PMCPMC3082928

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.