Trial reportJournal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology2011
Human dental pulp stem cells derived from different cryopreservation methods of human dental pulp tissues of diseased teeth.
Trial report in Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 43 citations in OpenAlex.
- Sex as a biological variable in human dental pulp stem cells: An exploratory epigenomic and transcriptomic comparison.Regenerative therapy · 2026Article
- Bone Tissue Bioengineering for Craniofacial and Dental Applications: Association of Deciduous Dental Pulp Stem Cells to Carbonated Hydroxyapatite.International journal of molecular sciences · 2026Article
- Intrinsic and extrinsic modulators of human dental pulp stem cells: advancing strategies for tissue engineering applications.Molecular biology reports · 2025Review
- Long-term cryopreservation of whole gingival tissue.Cell and tissue banking · 2024Article
- Research progress on optimization ofFrontiers in bioengineering and biotechnology · 2024Review
- Immunomodulatory Mechanism and Potential Application of Dental Pulp-Derived Stem Cells in Immune-Mediated Diseases.International journal of molecular sciences · 2023Review
- Application of cryopreservation to tooth germ transplantation for root development and tooth eruption.Scientific reports · 2021Article
- Cryopreservation of mesenchymal stem cells derived from dental pulp: a systematic review.Restorative dentistry & endodontics · 2021Article
- Vitrification of Dog Skin Tissue as a Source of Mesenchymal Stem Cells.BioMed research international · 2021Article
- Banking on teeth - Stem cells and the dental office.Biomedical journal · 2020Review
- Explant culture: An advantageous method for isolation of mesenchymal stem cells from human tissues.Cell proliferation · 2017Review
- Taking a bite out of spinal cord injury: do dental stem cells have the teeth for it?Cellular and molecular life sciences : CMLS · 2016Review
- Today prospects for tissue engineering therapeutic approach in dentistry.TheScientificWorldJournal · 2014Review
- Application of Stem Cell Technology in Dental Regenerative Medicine.Advances in wound care · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundSuccessful isolation of human dental pulp stem cells (hDPSCs) has been documented at least 120h after tooth extraction. Viable hDPSCs have been isolated chiefly from cryopreserved healthy molar teeth and their undigested dental pulp tissue. Isolation of hDPSCs from diseased but vital teeth after cryopreservation has not been reported. This study aimed to isolate hDPSCs from cryopreserved diseased but vital teeth of various tooth types. MATERIALS: Fifty tooth samples were divided into group A (n = 20) - freshly derived dental pulp tissues, group B (n = 20) - liquid nitrogen (liq N(2) )-stored dental pulp tissues and group C (n = 10) - liq N(2) -stored intact teeth. METHODS AND
resultsThe success rate for hDPSCs isolation was 100% for groups A and B and only 20% for group C. hDPSCs from all groups demonstrated self-renewal properties and similar multipotent potential characteristics of adipogenic, chondrogenic and osteogenic differentiation. In addition, hDPSCs showed high expression of bone-marrow mesenchymal stem-cell markers (CD29, CD90 and CD105) and very low expression of specific hematopoietic cells markers (CD14, CD34 and CD45).
conclusionOur results indicate that hDPSCs isolated from diseased but vital teeth of various tooth types can be stored in liq N(2) for future usage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.