ArticleJournal of oral rehabilitation2011
Changes in health complaints after removal of amalgam fillings.
Article in Journal of oral rehabilitation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00346944 (Health Effects From Removal of Amalgam Restorations in Patients With Symptoms Allegedly Related to Dental Amalgam - A Study of Patients Examined at the Dental Biomaterials Adverse Reaction Unit in 1993 to 1999), which is not on this map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Health Effects From Removal of Amalgam Restorations in Patients With Symptoms Allegedly Related to Dental Amalgam - A Study of Patients Examined at the Dental Biomaterials Adverse Reaction Unit in 1993 to 1999
Who cites it
12 citing papers in PubMed, 32 citations in OpenAlex.
- A Five-Year Follow-Up Study on the Removal of Dental Amalgam Restorations (Bergen Amalgam Trial): Examining Potential Confounding Factors and Effect Modification.Journal of oral rehabilitation · 2025Article
- Health complaints before and at one and five years after removal of dental amalgam restorations - data from a prospective cohort study in Norway.Acta odontologica Scandinavica · 2024Article
- Article
- Validity and responsiveness of EQ-5D-5L and SF-6D in patients with health complaints attributed to their amalgam fillings: a prospective cohort study of patients undergoing amalgam removal.Health and quality of life outcomes · 2021Article
- Use of complementary and alternative medicine in patients with health complaints attributed to former dental amalgam fillings.BMC complementary and alternative medicine · 2016Article
- Patients give meaning to changes in health complaints before, during and after the replacement of amalgam restorations.Evidence-based dentistry · 2015Article
- Multidisciplinary Management of An Unusual Isolated Alveolar Bone Infection- A Rare Case Report.Journal of clinical and diagnostic research : JCDR · 2015Article
- Patients' experiences of changes in health complaints before, during, and after removal of dental amalgam.International journal of qualitative studies on health and well-being · 2015Article
- Longitudinal analysis of the association between removal of dental amalgam, urine mercury and 14 self-reported health symptoms.Environmental health : a global access science source · 2014Article
- Reliance on social security benefits by Swedish patients with ill-health attributed to dental fillings: a register-based cohort study.BMC public health · 2012Article
- A safe protocol for amalgam removal.Journal of environmental and public health · 2012Review
- Clinical resolution of oral lichenoid lesions after amalgam replacement: A systematic review and meta-analysis of observational studies.Journal of oral biology and craniofacial researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the present study was to investigate whether removal of all amalgam fillings was associated with long-term changes in health complaints in a group of patients who attributed subjective health complaints to amalgam fillings. Patients previously examined at the Norwegian Dental Biomaterials Adverse Reaction Unit were included in the study and assigned to a treatment group (n = 20) and a reference group (n = 20). Participants in the treatment group had all amalgam fillings replaced with other restorative materials. Follow-ups took place 3 months, 1 and 3 years after removal of all amalgam fillings. There was no intervention in the reference group. Subjective health complaints were measured by numeric rating scales in both groups. Analysis of covariance was used to compare changes in health complaints over time in the two groups. In the treatment group, there were significant reductions in intra-oral and general health complaints from inclusion into study to the 3-year follow-up. In the reference group, changes in the same period were not significant. Comparisons between the groups showed that reductions in intra-oral and general health complaints in the treatment group were significantly different from the changes in the reference group. The mechanisms behind this remain to be identified. Reduced exposure to dental amalgam, patient-centred treatment and follow-ups, and elimination of worry are factors that may have influenced the results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.