ArticleNature methods2011
Next-generation sequencing to generate interactome datasets.
Article in Nature methods, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
148 citing papers in PubMed.
- FaNAC29: a novel gene positively regulating strawberry powdery mildew resistance.The New phytologist · 2026Article
- Explainable drug side effect prediction in central neural system via biologically informed graph neural network.Translational psychiatry · 2026Article
- Interspecies rice versus Arabidopsis thaliana protein-protein interactome profiling by touch-down overlapping PCR coupled with HiFi long-read sequencing.Journal of integrative plant biology · 2026Article
- The Unconventional Role of ABHD17A in Increasing the S-Palmitoylation and Antiviral Activity of IFITM1 by Downregulating ABHD16A.Biomolecules · 2025Article
- Global Protein Interactome Mapping in Rice Using Barcode-Indexed PCR Coupled with HiFi Long-Read Sequencing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A graph neural network-based approach for predicting SARS-CoV-2-human protein interactions from multiview data.PloS one · 2025Article
- Generating Biomedical Knowledge Graphs from Knowledge Bases, Registries, and Multiomic Data.bioRxiv : the preprint server for biology · 2024Article
- Massively parallel measurement of protein-protein interactions by sequencing using MP3-seq.Nature chemical biology · 2024Article
- Sesame Detection in Food Using DNA-Functionalized Gold Nanoparticles: A Sensitive, Rapid, and Cost-Effective Colorimetric Approach.Biosensors · 2024Article
- PETA: evaluating the impact of protein transfer learning with sub-word tokenization on downstream applications.Journal of cheminformatics · 2024Article
- Computational biology-based study of the molecular mechanism of spermidine amelioration of acute pancreatitis.Molecular diversity · 2024Article
- Standigm ASK™: knowledge graph and artificial intelligence platform applied to target discovery in idiopathic pulmonary fibrosis.Briefings in bioinformatics · 2024Article
- Understanding the molecular mechanisms of human diseases: the benefits of fission yeasts.Microbial cell (Graz, Austria) · 2024Article
- Molecular Modulators and Receptors of Selective Autophagy: Disease Implication and Identification Strategies.International journal of biological sciences · 2024Review
- In vivo versus in silico assessment of potentially pathogenic missense variants in human reproductive genes.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- A positive statistical benchmark to assess network agreement.Nature communications · 2023Article
- Evolutionary conservation of sequence motifs at sites of protein modification.The Journal of biological chemistry · 2023Article
- Next-Generation Yeast Two-Hybrid Screening to Discover Protein-Protein Interactions.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Deep variational graph autoencoders for novel host-directed therapy options against COVID-19.Artificial intelligence in medicine · 2022Article
- Adtrp regulates thermogenic activity of adipose tissue via mediating the secretion of S100b.Cellular and molecular life sciences : CMLS · 2022Article
88 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
Abstract
Next-generation sequencing has not been applied to protein-protein interactome network mapping so far because the association between the members of each interacting pair would not be maintained in en masse sequencing. We describe a massively parallel interactome-mapping pipeline, Stitch-seq, that combines PCR stitching with next-generation sequencing and used it to generate a new human interactome dataset. Stitch-seq is applicable to various interaction assays and should help expand interactome network mapping.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.