Evidence map›Paper›PMID 21515843›Full record

ArticleDiabetes care2011

Vitamin D status in relation to glucose metabolism and type 2 diabetes in septuagenarians.

Christine Dalgård, Maria Skaalum Petersen, Pal Weihe, Philippe Grandjean

Open access · hybridAbstract read
In one paragraph

Article in Diabetes care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 9 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 9 syntheses or guidelines pooled it, 130 citations in OpenAlex.

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  15. Transcriptome and metabolome changes induced by bitter melon (Journal of traditional and complementary medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Christine DalgårdInstitute of Public Health, Department of Environmental Medicine, University of Southern Denmark, Odense, Denmark. cdalgaard@health.sdu.dk
Maria Skaalum Petersen
Pal Weihe
Philippe Grandjean
University of Southern Denmark · DKUniversity of the Faroe Islands · FO

Funding

Health Effects of Lifetime Exposure to Food ContaminantsR01ES013692 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI GRANDJEAN, PHILIPPE ADAM · 2006 to 2009
$1.1M
NIEHS NIH HHS ES013692NIEHS NIH HHS R01 ES013692
6 · The paper itself

Abstract

objectiveVitamin D deficiency is thought to be a risk factor for development of type 2 diabetes, and elderly subjects at northern latitudes may therefore be at particular risk. RESEARCH DESIGN AND

methodsVitamin D status was assessed from serum concentrations of 25-hydroxyvitamin D(3) [25(OH)D(3)] in 668 Faroese residents aged 70-74 years (64% of eligible population). We determined type 2 diabetes prevalence from past medical histories, fasting plasma concentrations of glucose, and/or glycosylated hemoglobin (HbA(1c)).

resultsWe observed 70 (11%) new type 2 diabetic subjects, whereas 88 (13%) were previously diagnosed. Having vitamin D status <50 nmol/L doubled the risk of newly diagnosed type 2 diabetes after adjustment for BMI, sex, exposure to polychlorinated biphenyls, serum triacylglyceride concentration, serum HDL concentration, smoking status, and month of blood sampling. Furthermore, the HbA(1c) concentration decreased at higher serum 25(OH)D(3) concentrations independent of covariates.

conclusionsIn elderly subjects, vitamin D sufficiency may provide protection against type 2 diabetes. Because the study is cross-sectional, intervention studies are needed to elucidate whether vitamin D could be used to prevent development of type 2 diabetes.

Indexed as

AgedBlood GlucoseCalcifediolCross-Sectional StudiesDenmarkDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHumansMaleVitamin D DeficiencyBlood GlucoseCalcifediolGlycated Hemoglobin

Identifiers

PMID21515843
PMCPMC3114341
OpenAlexW2054643391

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.