Evidence map›Paper›PMID 21515762›Full record

ArticleJournal of bacteriology2011

Genomes of two chronological isolates (Helicobacter pylori 2017 and 2018) of the West African Helicobacter pylori strain 908 obtained from a single patient.

Tiruvayipati Suma Avasthi, Singamaneni Haritha Devi, Todd D Taylor, Narender Kumar, Ramani Baddam, Shinji Kondo, Yutaka Suzuki, Hervé Lamouliatte, Francis Mégraud, Niyaz Ahmed

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  3. A SystematicCurrent genomics · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Tiruvayipati Suma AvasthiDepartment of Biotechnology, University of Hyderabad, Gachibowli, Hyderabad, India.
Singamaneni Haritha Devi
Todd D Taylor
Narender Kumar
Ramani Baddam
Shinji Kondo
Yutaka Suzuki
Hervé Lamouliatte
Francis Mégraud
Niyaz Ahmed
University of Hyderabad · INBordeaux Population Health · FRHôpital Saint-André · FRThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diverse clinical outcomes of colonization by Helicobacter pylori reflect the need to understand the genomic rearrangements enabling the bacterium to adapt to host niches and exhibit varied colonization/virulence potential. We describe the genome sequences of the two serial isolates, H. pylori 2017 and 2018 (the chronological subclones of H. pylori 908), cultured in 2003 from the antrum and corpus, respectively, of an African patient who suffered from recrudescent duodenal ulcer disease. When compared with the genome of the parent strain, 908 (isolated from the antrum of the same patient in 1994), the genome sequences revealed genomic alterations relevant to virulence optimization or host-specific adaptation.

Indexed as

Genome, BacterialAfricaDNA, BacterialDuodenal UlcerGastric MucosaHelicobacter InfectionsHelicobacter pyloriHumansMolecular Sequence DataSequence Analysis, DNAStomachVirulence FactorsDNA, BacterialVirulence Factors

Identifiers

PMID21515762
PMCPMC3133283
OpenAlexW2116108792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.