Evidence map›Paper›PMID 21515168›Full record

ArticleBiomaterials2011

Advantages of RGD peptides for directing cell association with biomaterials.

Susan L Bellis

Abstract read
In one paragraph

Article in Biomaterials, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 241 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
241citing papers in PubMed, 2 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

241 citing papers in PubMed, 2 syntheses or guidelines pooled it, 714 citations in OpenAlex.

  1. Pooled it
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  11. Tissue-specific gene delivery approaches.Bioengineering & translational medicine · 2026
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181 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Susan L BellisDepartment of Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. bellis@uab.edu
University of Alabama at Birmingham · US

Funding

Functionalizing Hydroxyapatite With Proadhesive PeptidesR01AR051539 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BELLIS, SUSAN L · 2005 to 2008
$1.0M
NIAMS NIH HHS R01 AR051539
6 · The paper itself

Abstract

Despite many years of in vitro research confirming the effectiveness of RGD in promoting cell attachment to a wide variety of biomaterials, animal studies evaluating tissue responses to implanted RGD-functionalized substrates have yielded more variable results. The goals of this report are to present some of the reasons why cell culture studies may not always reliably predict in vivo responses, and more importantly, to highlight potential applications that may benefit from the use of RGD peptides.

Indexed as

Biocompatible MaterialsCell AdhesionCells, CulturedHumansOligopeptidesarginyl-glycyl-aspartic acidBiocompatible MaterialsOligopeptides

Identifiers

PMID21515168
PMCPMC3091033
OpenAlexW2042261220

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.