Evidence map›Paper›PMID 21515003›Full record

Trial reportDrug and alcohol dependence2011

Oral tobacco products: preference and effects among smokers.

Dorothy K Hatsukami, Joni Jensen, Amanda Anderson, Berry Broadbent, Sharon Allen, Yan Zhang, Herb Severson

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Smoking a Dangerous Addiction: A Systematic Review on an Underrated Risk Factor for Oral Diseases.International journal of environmental research and public health · 2021
    Pooled it
  2. Systematic Review of Tobacco Use after Lung or Head/Neck Cancer Diagnosis: Results and Recommendations for Future Research.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015
    Pooled it
  3. Acute effects of snus in never-tobacco users: a pilot study.The American journal of drug and alcohol abuse · 2018
    Trial
  4. A Naturalistic, Randomized Pilot Trial of E-Cigarettes: Uptake, Exposure, and Behavioral Effects.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2017
    Trial
  5. Trial
  6. Trial
  7. Trial
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  9. Trial
  10. Brief, instructional smokeless tobacco use among cigarette smokers who do not intend to quit: a pilot randomized clinical trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2014
    Trial
  11. Article
  12. Article
  13. Article
  14. Consortium on Methods Evaluating Tobacco: Research Tools to Inform US Food and Drug Administration Regulation of Snus.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
    Review
  15. Characteristics of "American Snus" and Swedish Snus Products for Sale in Massachusetts, USA.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
    Article
  16. Using Electrophysiological Measures to Assess the Consumer Acceptability of Smokeless Tobacco Products.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Article
  17. Do Socioeconomic Risk Factors for Cigarette Smoking Extend to Smokeless Tobacco Use?Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Article
  18. Nicotine Absorption from Smokeless Tobacco Modified to Adjust pH.Journal of addiction research & therapy · 2014
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dorothy K HatsukamiDepartment of Psychiatry, University of Minnesota, 717 Delaware SE, Minneapolis, MN 55414, USA. hatsu001@umn.edu
Joni Jensen
Amanda Anderson
Berry Broadbent
Sharon Allen
Yan Zhang
Herb Severson

Funding

Evaluation of Oral Tobacco as a Harm Reduction Method for SmokersR01CA135884 · NCI · UNIVERSITY OF MINNESOTA · PI HATSUKAMI, DOROTHY K · 2008 to 2013
$2.7M
NCI NIH HHS R01 CA135884NCI NIH HHS R01-CA135884
6 · The paper itself

Abstract

backgroundRecently, oral tobacco products have been marketed specifically towards cigarette smokers. These products come in different nicotine doses and formulations (snus vs. lozenge). To date, little research has been conducted to determine how smokers respond to these products. The goal of this study was to examine if smokers prefer certain oral tobacco products based on their specific characteristics.

methodsSmokers interested in quitting underwent a sampling phase and a treatment phase. The sampling phase consisted of testing five different products varying in nicotine dose (high vs. moderate vs. low) and formulation (snus vs. lozenge): General Snus, Camel Snus, Marlboro Snus, Stonewall and Ariva. Each product was sampled in the natural environment on separate days. At the end of the sampling period, subjects chose which product they would use during the 2-week cigarette abstinence phase.

resultsGeneral Snus (high nicotine) was not preferred by any smoker. No significant differences in preferences were observed across the other tobacco products. During the smoking cessation phase, Camel Snus was generally associated with greater craving relief and satisfaction, reduced use of cigarettes, and greater abstinence during follow-up compared to other products.

conclusionThere were no differences in preferences for four of the five oral tobacco products but higher nicotine oral tobacco products were associated with better cessation outcomes among smokers who chose these products.

Indexed as

Tobacco, SmokelessAdultFemaleHumansMaleNicotineSmokingSmoking CessationSurveys and QuestionnairesNicotine

Identifiers

PMID21515003
PMCPMC3164739

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.