ArticleClinical biomechanics (Bristol, Avon)2011
Effects of progressive resistance strength training on knee biomechanics during single leg step-up in persons with mild knee osteoarthritis.
Article in Clinical biomechanics (Bristol, Avon), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02798900 (The Effect of a Functional Task-training Program Combined With Therapeutic Ultrasound on Pain, Strength, Gait Biomechanics and Functionality in Adults With Hip Osteoarthritis), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of a Functional Task-training Program Combined With Therapeutic Ultrasound on Pain, Strength, Gait Biomechanics and Functionality in Adults With Hip Osteoarthritis
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Exercise for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2024Pooled it
- Exercise for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2015Pooled it
- Reductions in co-contraction following neuromuscular re-education in people with knee osteoarthritis.BMC musculoskeletal disorders · 2016Trial
- No effects of a 12-week supervised exercise therapy program on gait in patients with mild to moderate osteoarthritis: a secondary analysis of a randomized trial.Journal of negative results in biomedicine · 2015Trial
- Comparison of neuromuscular and quadriceps strengthening exercise in the treatment of varus malaligned knees with medial knee osteoarthritis: a randomised controlled trial protocol.BMC musculoskeletal disorders · 2011Trial
- Reduced Muscle Strength Can Alter the Impact of Gait Modifications on Knee Cartilage Mechanics.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Optimal exercise modalities and doses for therapeutic management of osteoarthritis of the knee.Frontiers in aging · 2025Review
- Reference intervals for knee functions specific to outpatients with knee osteoarthritis: a cross-sectional study.BMC sports science, medicine & rehabilitation · 2024Article
- Efficacy of Mulligan joint mobilizations and trunk stabilization exercises versus isometric knee strengthening in the management of knee osteoarthritis: a randomized controlled trial.BMC sports science, medicine & rehabilitation · 2024Article
- Is Quadriceps-Strengthening Exercises (QSE) in Medial-Compartment Knee Osteoarthritis with Neutral and Varus Malalignment a Paradox? - A Risk-Appraisal of Strength-Training on Disease Progression.Malaysian orthopaedic journal · 2024Article
- High Compliance with the 11+ Injury Prevention Program Results in Better Win-Loss Records.International journal of sports physical therapy · 2023Article
- An Analysis of Lower Limb Coordination Variability in Unilateral Tasks in Healthy Adults: A Possible Prognostic Tool.Frontiers in bioengineering and biotechnology · 2022Article
- Consensus on non-pharmacological interventions for mild and moderate knee osteoarthritis among stakeholders/experts of various disciplines is still elusive -A preliminary report.Journal of clinical orthopaedics and trauma · 2019Article
- Sagittal and Frontal Plane Gait Initiation Kinetics in Healthy, Young Subjects.Journal of human kinetics · 2019Article
- Postoperative time dependent tibiofemoral articular cartilage contact kinematics during step-up after ACL reconstruction.Journal of biomechanics · 2016Article
- Article
- Kinematic characteristics of the tibiofemoral joint during a step-up activity.Gait & posture · 2013Article
- Current interventions in the management of knee osteoarthritis.Journal of pharmacy & bioallied sciences · 2013Article
- Resistance exercise for knee osteoarthritis.PM & R : the journal of injury, function, and rehabilitation · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThe goal of this study was to determine if increasing strength in primary knee extensors and flexors would directly affect net knee joint moments during a common functional task in persons with knee osteoarthritis.
methodsAn exploratory single sample clinical trial with pre-post treatment measures was used to study volunteers with clinical diagnosis of mild knee osteoarthritis (OA) in one knee. Subjects participated in an individually supervised training program 3 times a week for eight weeks consisting of progressive resistive exercises for knee extensors and knee flexors. Pre and post training outcome assessments included: 1. Net internal knee joint moments, 2. Electromyography of primary knee extensors and flexors, and 3. Self-report measures of knee pain and function. The distribution of lower extremity joint moments as a percent of the total support moment was also investigated.
findingsPain, symptoms, activities of daily life, quality of life, stiffness, and function scores showed significant improvement following strength training. Knee internal valgus and hip internal rotation moments showed increasing but non-statistically significant changes post-training. There were no significant differences in muscle co-contraction activation of the Quadriceps and Hamstrings.
interpretationWhile exercise continues to be an important element of OA management, the results of this study suggest improvements in function, pain, and other symptoms, as a result of strength training may not be causally related to specific biomechanical changes in net joint moments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.