Evidence map›Paper›PMID 21512730›Full record

ArticleInternational journal of hematology2011

Early electrocardiographic evaluation of atrial fibrillation risk in beta-thalassemia major patients.

Vincenzo Russo, Anna Rago, Bruno Pannone, Federica Di Meo, Andrea Antonio Papa, Maria Carolina Mayer, Anna Spasiano, Maria Giovanna Russo, Paolo Golino, Raffaele Calabrò and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of hematology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Cardiovascular magnetic resonance native TJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020
    Pooled it
  2. The effect of atrial preference pacing on atrial fibrillation electrophysiological substrate in Myotonic Dystrophy type 1 population.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2014
    Trial
  3. Atrial fibrillation burden in Myotonic Dystrophy type 1 patients implanted with dual chamber pacemaker: the efficacy of the overdrive atrial algorithm at 2 year follow-up.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2013
    Trial
  4. Review
  5. The role of iron overload and ferroptosis in arrhythmia pathogenesis.International journal of cardiology. Heart & vasculature · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Complete resolution of left atrial appendage thrombosis with oral dabigatran etexilate in a patient with Myotonic Dystrophy type 1 and atrial fibrillation.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2017
    Article
  12. The role of the atrial electromechanical delay in predicting atrial fibrillation in beta-thalassemia major patients.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2017
    Article
  13. Voltage-directed cavo-tricuspid isthmus ablation using a novel ablation catheter mapping technology in a myotonic dystrophy type I patient.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2016
    Article
  14. Increased heterogeneity of ventricular repolarization in myotonic dystrophy type 1 population.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2016
    Article
  15. Electrocardiographic Presentation, Cardiac Arrhythmias, and Their Management in β-Thalassemia Major Patients.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2016
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Vincenzo RussoDepartment of Cardiology, Second University of Naples, Via Leonardo Bianchi, 80100, Naples, Italy. v.p.russo@libero.it.
Anna RagoDepartment of Cardiology, Second University of Naples, Via Leonardo Bianchi, 80100, Naples, Italy.
Bruno PannoneInternal Medicine Unit, Cardarelli Hospital, Naples, Italy.
Federica Di MeoDepartment of Cardiology, Second University of Naples, Via Leonardo Bianchi, 80100, Naples, Italy.
Andrea Antonio PapaDepartment of Cardiology, Second University of Naples, Via Leonardo Bianchi, 80100, Naples, Italy.
Maria Carolina MayerInternal Medicine Unit, Cardarelli Hospital, Naples, Italy.
Anna SpasianoMicrocitemia Center, Cardarelli Hospital, Naples, Italy.
Maria Giovanna RussoDepartment of Cardiology, Second University of Naples, Via Leonardo Bianchi, 80100, Naples, Italy.
Paolo GolinoDepartment of Cardiology, Second University of Naples, Via Leonardo Bianchi, 80100, Naples, Italy.
Raffaele CalabròDepartment of Cardiology, Second University of Naples, Via Leonardo Bianchi, 80100, Naples, Italy.
Gerardo NigroDepartment of Cardiology, Second University of Naples, Via Leonardo Bianchi, 80100, Naples, Italy.
University of Campania "Luigi Vanvitelli" · ITUniversity of Naples Federico II · ITFatebenefratelli Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although previous studies have documented a variety of electrocardiogram abnormalities in beta-thalassemia major (β-TM), little is known about P-wave dispersion (PD), an independent risk factor for development of atrial fibrillation. The aim of our study was to evaluate PD in β-TM patients with conserved systolic and diastolic functions. The study involved 40 β-TM patients (age 37.5 ± 10.2; 33 M) and 40 healthy subjects used as controls, matched for age and gender. PD was carefully measured using a 12-lead electrocardiogram. Cardiac iron levels were measured by cardiac magnetic resonance T2 star (CMR T2*) imaging. Comparing to the healthy control group, β-TM group presented increased values of the PD (40.1 ± 12.9 vs. 24 ± 7 ms; P < 0.004) and decreased CMR T2* imaging (29 ± 15 vs. 55 ± 13 ms; P = 0.03). We found a significant correlation between PD and CMR T2* values. Our study showed a significant increase of PD in β-TM patients with conserved systolic and diastolic cardiac functions. Our results indicate that PD is correlated to myocardial iron deposit, as assessed by CMR T2* imaging.

Indexed as

ElectrocardiographyAdultAtrial Fibrillationbeta-ThalassemiaFemaleHeartHumansMagnetic Resonance ImagingMaleMiddle AgedRisk Factors

Identifiers

PMID21512730
OpenAlexW1993334971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.