ReviewPlant signaling & behavior2011
The aspartate-family pathway of plants: linking production of essential amino acids with energy and stress regulation.
Review in Plant signaling & behavior, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 155 citations in OpenAlex.
- Calcium, methyl jasmonate and their combined foliar applications: Influence on Tempranillo grape amino acids composition over two seasons.Journal of the science of food and agriculture · 2026Article
- Lysine Biosynthesis Defines a Metabolic Checkpoint for Gibberellin-Mediated Growth in Arabidopsis thaliana.Plant, cell & environment · 2026Article
- Metabolomic profiling of diatoms reveals distinct impacts of silver nanoparticles and ions.Environmental science. Nano · 2026Article
- Genome-wide identification and characterization of the RNAi gene families in Brassica rapa L. highlighting their regulatory components and underlying functions involving crop improvement.BMC genomic data · 2026Article
- Genotypic variation in maize leaf senescence after ear removal is caused by excess accumulation of photosynthates.Plant physiology · 2026Article
- Cultivar-specific metabolomic and morpho-physiological responses reveal distinct salt tolerance mechanisms in rice (Oryza sativa L.).BMC plant biology · 2026Article
- Phosphorus Alters the Metabolism of Sugars and Amino Acids in Elite Wheat Grains.Plants (Basel, Switzerland) · 2025Article
- Asparagine Synthetase GenePlants (Basel, Switzerland) · 2025Article
- Small-scale heterogeneity of soil properties in farmland affected fava beans growth through rhizosphere differential metabolites and microorganisms.Environmental microbiome · 2025Article
- UV-B Stress-Triggered Amino Acid Reprogramming and ABA-Mediated Hormonal Crosstalk inPlants (Basel, Switzerland) · 2024Article
- Identification of mungbean yellow mosaic India virus and susceptibility-related metabolites in the apoplast of mung bean leaves.Plant cell reports · 2024Article
- Article
- Assessing sequence variation, haplotype analysis and molecular characterisation of aspartate kinase2 (ask2) gene regulating methionine biosynthesis in diverse maize inbreds.Molecular genetics and genomics : MGG · 2024Article
- OsbZIP18 Is a Positive Regulator of Phenylpropanoid and Flavonoid Biosynthesis under UV-B Radiation in Rice.Plants (Basel, Switzerland) · 2024Article
- Differential gene expression provides leads to environmentally regulated soybean seed protein content.Frontiers in plant science · 2023Article
- Proliferation and Metabolic Profiling ofACS omega · 2022Article
- UV-B Irradiation to Amino Acids and Carbohydrate Metabolism inPlants (Basel, Switzerland) · 2022Article
- 4D genetic networks reveal the genetic basis of metabolites and seed oil-related traits in 398 soybean RILs.Biotechnology for biofuels and bioproducts · 2022Article
- Article
- Investigation of Possible Changes Induced by RNA Silencing in Some Leaf Metabolites of Transgenic Sugar Beet Events.Food chemistry. Molecular sciences · 2022Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Asp family pathway of plants is highly important from a nutritional standpoint because it leads to the synthesis of the four essential amino acids Lys, Thr, Met and Ile. These amino acids are not synthesized by human and its monogastric livestock and should be supplemented in their diets. Among the Asp-family amino acids, Lys is considered as the nutritionally most important essential amino acid because its level is most limiting in cereal grains, representing the largest source of plant foods and feeds worldwide. Metabolic engineering approaches led to significant increase in Lys level in seeds by enhancing its synthesis and reducing its catabolism. However, results from the model plant Arabidopsis showed that this approach may retard seed germination due to a major negative effect on the levels of a number of TCA cycle metabolites that associate with cellular energy. In the present review, we discuss the regulatory metabolic link of the Asp-family pathway with the TCA cycle and its biological significance upon exposure to stress conditions that cause energy deprivation. In addition, we also discuss how deep understanding of the regulatory metabolic link of the Asp-family pathway with energy and stress regulation can be used to improve Lys level in seeds of important crop species, minimizing the interference with the cellular energy status and plant-stress interaction. This review thus provides an example showing how deep understanding the inter-regulation of metabolism with plant stress physiology can lead to successful nutritional improvements with minimal negative effect on plant growth and response to stressful environments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.