ArticleScience (New York, N.Y.)2011
Medicine. Progranulin resolves inflammation.
Article in Science (New York, N.Y.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- Analysis of progranulin concentration in corneal epithelium and tears as a possible biomarker in the clinical diagnosis and progression of keratoconus.International ophthalmology · 2025Article
- The Role of Progranulin (PGRN) in the Pathogenesis of Ischemic Stroke.Cellular and molecular neurobiology · 2023Review
- Progranulin Promotes Functional Recovery in Rats with Acute Spinal Cord Injury via Autophagy-Induced Anti-inflammatory Microglial Polarization.Molecular neurobiology · 2022Article
- Decoding lymphomyeloid divergence and immune hyporesponsiveness in G-CSF-primed human bone marrow by single-cell RNA-seq.Cell discovery · 2022Article
- Progranulin Protects Against Airway Remodeling Through the Modulation of Autophagy via HMGB1 Suppression in House Dust Mite-Induced Chronic Asthma.Journal of inflammation research · 2021Article
- The Role of a Proprotein Convertase Inhibitor in Reactivation of Tumor-Associated Macrophages and Inhibition of Glioma Growth.Molecular therapy oncolytics · 2020Article
- Progranulin Administration Attenuates β-Amyloid Deposition in the Hippocampus of 5xFAD Mice Through Modulating BACE1 Expression and Microglial Phagocytosis.Frontiers in cellular neuroscience · 2020Article
- Progranulin attenuates liver fibrosis by downregulating the inflammatory response.Cell death & disease · 2019Article
- Disease-modifying effects of metabolic perturbations in ALS/FTLD.Molecular neurodegeneration · 2018Review
- Role of clusterin/progranulin in toluene diisocyanate-induced occupational asthma.Experimental & molecular medicine · 2018Article
- Allantopyrone A interferes with multiple components of the TNF receptor 1 complex and blocks RIP1 modifications in the TNF-α-induced signaling pathway.The Journal of antibiotics · 2017Article
- Review: Novel Insights Into Tumor Necrosis Factor Receptor, Death Receptor 3, and Progranulin Pathways in Arthritis and Bone Remodeling.Arthritis & rheumatology (Hoboken, N.J.) · 2016Review
- The Role of PGRN in Alzheimer's Disease.Molecular neurobiology · 2016Review
- Extracellular matrix protein 1, a direct targeting molecule of parathyroid hormone-related peptide, negatively regulates chondrogenesis and endochondral ossification via associating with progranulin growth factor.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2016Article
- Progranulin suppresses titanium particle induced inflammatory osteolysis by targeting TNFα signaling.Scientific reports · 2016Article
- The novel adipokine progranulin counteracts IL-1 and TLR4-driven inflammatory response in human and murine chondrocytes via TNFR1.Scientific reports · 2016Article
- Progranulin protects against osteoarthritis through interacting with TNF-α and β-Catenin signalling.Annals of the rheumatic diseases · 2015Article
- New discovery rarely runs smooth: an update on progranulin/TNFR interactions.Protein & cell · 2015Review
- Transmembrane TNF-TNFR2 Impairs Th17 Differentiation by Promoting Il2 Expression.Journal of immunology (Baltimore, Md. : 1950) · 2015Article
- PGRN induces impaired insulin sensitivity and defective autophagy in hepatic insulin resistance.Molecular endocrinology (Baltimore, Md.) · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.