SynthesisCephalalgia : an international journal of headache2011
Migraine, migraine aura, and cervical artery dissection: a systematic review and meta-analysis.
Synthesis in Cephalalgia : an international journal of headache, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed, 4 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- Risk factors for cervical artery dissection: a systematic review with meta-analysis.Stroke and vascular neurology · 2026Pooled it
- Genetically proxied liability to migraine and risk of intracranial aneurysm and subarachnoid hemorrhage.Headache · 2025Pooled it
- Migraine and the risk of cervical artery dissection: A systematic review and meta-analysis.European stroke journal · 2023Pooled it
- The Impact of Spinal Manipulation on Migraine Pain and Disability: A Systematic Review and Meta-Analysis.Headache · 2019Pooled it
- Migraine in Young Stroke Patients-Better Outcomes Despite Distinct Risk Profiles: Insights From the STROKE-CARD-Study.European journal of neurology · 2026Observational
- Serum tumor necrosis factor-α levels in migraine: a registry for migraine (REFORM) study.Pain reports · 2026Article
- Tsunamis hiding in plain sight: spreading depression in clinical neurology.Nature reviews. Neurology · 2026Review
- Prevalence of Intracranial and Cervical Artery Abnormalities in Patients with Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders Presenting to an Academic Headache Clinic.Neurology international · 2026Article
- Article
- Spontaneous Coronary Artery Dissection: A Narrative Review of Epidemiology and Public Health Implications.Medicina (Kaunas, Lithuania) · 2025Review
- Headaches attributed to cranial and cervical artery dissections.The journal of headache and pain · 2025Review
- Carotid artery dissection recanalization: imaging modalities, influencing factors, and therapeutic perspectives.Frontiers in neurology · 2025Review
- Beyond vascular recanalization: precision medicine in cervical artery dissection guided by multiple mechanisms and multimodal imaging for brain functional recovery.Frontiers in physiology · 2025Review
- Increased risks of retinal vascular occlusion in patients with migraine and the protective effects of migraine treatment: a population-based retrospective cohort study.Scientific reports · 2024Article
- Association between vertebral artery dominance and basilar artery curvature in migraineurs: an anatomical magnetic resonance imaging study.The neuroradiology journal · 2024Article
- Cervical Artery Dissections-A Demographical Analysis of Risk Factors, Clinical Characteristics Treatment Procedures, and Outcomes-A Single Centre Study of 54 Consecutive Cases.Journal of personalized medicine · 2023Article
- Dobutamine-induced alternations in cerebral blood flow of healthy adults: a 3D pseudocontinuous arterial spin labeling study.BMC medicine · 2023Article
- Advances in Management of the Stroke Etiology One-Percenters.Current neurology and neuroscience reports · 2023Review
- Microembolism and Other Links Between Migraine and Stroke: Clinical and Pathophysiologic Update.Neurology · 2023Review
- Vertebrobasilar artery elongation in migraine-a retrospective cross-sectional study.Acta neurologica Belgica · 2023Article
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
Abstract
objectiveWe evaluated the current evidence on the association between migraine, including aura status, and cervical artery dissection.
methodsWe performed a systematic review and meta-analysis of studies investigating the association between migraine or migraine subtypes (e.g. migraine with aura) and cervical artery dissection published through October 2010.
resultsWe identified five case-control studies investigating the association between migraine and cervical artery dissection. In pooled analysis, migraine doubled the risk of cervical artery dissection (pooled odds ratio [OR]=2.06, 95% confidence interval [CI] 1.33-3.19). All studies allowed evaluation of migraine aura status. While the effect estimate for migraine without aura (pooled OR=1.94, 95% CI 1.21-3.10) was similar to overall migraine, the association was weaker for migraine with aura (pooled OR= 1.50, 95% CI 0.76-2.96). However, there is no evidence that aura status significantly modifies the association between migraine and cervical artery dissection (meta-regression on aura status p= .58). The risk does not appear to differ between women and men; however, only few studies presented gender-specific data. Heterogeneity among studies was low to moderate.
conclusionIn this meta-analysis migraine is associated with a two-fold increased risk of cervical artery dissection. This risk does not appear to significantly differ by migraine aura status or gender.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.