ReviewFungal genetics and biology : FG & B2011
Milestones in Candida albicans gene manipulation.
Review in Fungal genetics and biology : FG & B, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Candida albicans PPR proteins are required for the expression of respiratory Complex I subunits.Genetics · 2024Article
- Ten decadal advances in fungal biology leading towards human well-being.Fungal diversity · 2022Review
- SAGA Complex Subunits inFrontiers in cellular and infection microbiology · 2022Article
- Pervasive transcription of the mitochondrial genome inRNA biology · 2021Article
- Targeted Genetic Changes in Candida albicans Using Transient CRISPR-Cas9 Expression.Current protocols · 2021Article
- Transformation of Cryptococcus neoformans by electroporation using a transient CRISPR-Cas9 expression (TRACE) system.Fungal genetics and biology : FG & B · 2020Article
- CRISPR-Based Genetic Manipulation ofFrontiers in genome editing · 2020Review
- The CRISPR toolbox in medical mycology: State of the art and perspectives.PLoS pathogens · 2020Review
- Article
- Genome-wide functional analysis in Candida albicans.Virulence · 2017Review
- New "haploid biofilm model" unravels IRA2 as a novel regulator of Candida albicans biofilm formation.Scientific reports · 2015Article
- Fungal model systems and the elucidation of pathogenicity determinants.Fungal genetics and biology : FG & B · 2014Review
- Sulfone derivatives reduce growth, adhesion and aspartic protease SAP2 gene expression.World journal of microbiology & biotechnology · 2014Article
- Review
- Article
- Emerging and emerged pathogenic Candida species: beyond the Candida albicans paradigm.PLoS pathogens · 2013Review
- Systems biology of fungal infection.Frontiers in microbiology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
In the United States, candidemia is one of the most common hospital-acquired infections and is estimated to cause 10,000 deaths per year. The species Candida albicans is responsible for the majority of these cases. As C. albicans is capable of developing resistance against the currently available drugs, understanding the molecular basis of drug resistance, finding new cellular targets, and further understanding the overall mechanism of C. albicans pathogenesis are important goals. To study this pathogen it is advantageous to manipulate its genome. Numerous strategies of C. albicans gene manipulation have been introduced. This review evaluates a majority of these strategies and should be a helpful guide for researchers to identify gene targeting strategies to suit their requirements.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.