Evidence map›Paper›PMID 21510657›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2011

Voltage-controlled metal binding on polyelectrolyte-functionalized nanopores.

Paolo Actis, Boaz Vilozny, R Adam Seger, Xiang Li, Olufisayo Jejelowo, Marguerite Rinaudo, Nader Pourmand

Abstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Characterization of a Splice Variant inNeurology. Genetics · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Nanoneedle-Based Materials for Intracellular Studies.Advances in experimental medicine and biology · 2021
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Rectification of nanopores at surfaces.Journal of the American Chemical Society · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paolo ActisDepartment of Biomolecular Engineering, University of California Santa Cruz, 1156 High Street, Santa Cruz, California 95064, United States.
Boaz Vilozny
R Adam Seger
Xiang Li
Olufisayo Jejelowo
Marguerite Rinaudo
Nader Pourmand

Funding

WHOLE YEAST GENOME TRANSCRIPTIONAL AND FUNCTIONAL GENE MAPS--A FEASIBILITY STUDYP01HG000205 · NHGRI · STANFORD UNIVERSITY · PI DAVIS, RONALD WAYNE, HOWE, ROGER THOMAS · 1990 to 2016
$120.9M
NHGRI NIH HHS P01 HG000205NHGRI NIH HHS P01-HG000205
6 · The paper itself

Abstract

Most of the research in the field of nanopore-based platforms is focused on monitoring ion currents and forces as individual molecules translocate through the nanopore. Molecular gating, however, can occur when target analytes interact with receptors appended to the nanopore surface. Here we show that a solid state nanopore functionalized with polyelectrolytes can reversibly bind metal ions, resulting in a reversible, real-time signal that is concentration dependent. Functionalization of the sensor is based on electrostatic interactions, requires no covalent bond formation, and can be monitored in real time. Furthermore, we demonstrate how the applied voltage can be employed to tune the binding properties of the sensor. The sensor has wide-ranging applications and, its simplest incarnation can be used to study binding thermodynamics using purely electrical measurements with no need for labeling.

Indexed as

ElectricityNanoporesBiosensing TechniquesChitosanElectrolytesHydrogen-Ion ConcentrationMetalsPolymersReproducibility of ResultsTime FactorsChitosanElectrolytesMetalsPolymers

Identifiers

PMID21510657
PMCPMC3099346

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.