ArticleHippocampus2012
Head direction cells in the postsubiculum do not show replay of prior waking sequences during sleep.
Article in Hippocampus, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Phase Precession Relative to Turning Angle in Theta-Modulated Head Direction Cells.Hippocampus · 2025Article
- Article
- On the methods for reactivation and replay analysis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- The content of hippocampal "replay".Hippocampus · 2020Review
- The intrinsic attractor manifold and population dynamics of a canonical cognitive circuit across waking and sleep.Nature neuroscience · 2019Article
- Why Isn't the Head Direction System Necessary for Direction? Lessons From the Lateral Mammillary Nuclei.Frontiers in neural circuits · 2019Article
- Retrosplenial and postsubicular head direction cells compared during visual landmark discrimination.Brain and neuroscience advances · 2017Article
- Internally organized mechanisms of the head direction sense.Nature neuroscience · 2015Article
- Medial entorhinal grid cells and head direction cells rotate with a T-maze more often during less recently experienced rotations.Cerebral cortex (New York, N.Y. : 1991) · 2014Article
- Respiratory cycle entrainment of septal neurons mediates the fast coupling of sniffing rate and hippocampal theta rhythm.The European journal of neuroscience · 2014Article
- Modeling of grid cell activity demonstrates in vivo entorhinal 'look-ahead' properties.Neuroscience · 2013Article
- Segregation of cortical head direction cell assemblies on alternating θ cycles.Nature neuroscience · 2013Article
- About sleep's role in memory.Physiological reviews · 2013Review
- Voltage dependence of subthreshold resonance frequency in layer II of medial entorhinal cortex.Hippocampus · 2012Article
- Fear conditioning is disrupted by damage to the postsubiculum.Hippocampus · 2012Article
- Reduced spiking in entorhinal cortex during the delay period of a cued spatial response task.Learning & memory (Cold Spring Harbor, N.Y.) · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
During slow-wave sleep (SWS) and rapid eye movement (REM) sleep, hippocampal place cells in the rat show replay of sequences previously observed during waking. We tested the hypothesis from computational modeling that the temporal structure of REM sleep replay could arise from an interplay of place cells with head direction cells in the postsubiculum. Physiological single-unit recording was performed simultaneously from five or more head direction or place by head direction cells in the postsubiculum during running on a circular track allowing sampling of a full range of head directions, and during sleep periods before and after running on the circular track. Data analysis compared the spiking activity during individual REM periods with waking as in previous analysis procedures for REM sleep. We also used a new procedure comparing groups of similar runs during waking with REM sleep periods. There was no consistent evidence for a statistically significant correlation of the temporal structure of spiking during REM sleep with spiking during waking running periods. Thus, the spiking activity of head direction cells during REM sleep does not show replay of head direction cell activity occurring during a previous waking period of running on the task. In addition, we compared the spiking of postsubiculum neurons during hippocampal sharp wave ripple events. We show that head direction cells are not activated during sharp wave ripples, whereas neurons responsive to place in the postsubiculum show reliable spiking at ripple events.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.