Evidence map›Paper›PMID 21509771›Full record

ArticleCancer2011

Head and neck cancer-specific survival based on socioeconomic status in Asians and Pacific Islanders.

Karen P Chu, Sarah Shema, Simon Wu, Scarlett L Gomez, Ellen T Chang, Quynh-Thu Le

Open access · greenAbstract read
In one paragraph

Article in Cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Institutional clinical trial accrual volume and survival of patients with head and neck cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2015
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  15. Pre-treatment psychoeducational intervention and outcomes in head and neck cancer patients undergoing radiotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  16. Liver Cancer Incidence and Area-Level Geographic Disparities in Pennsylvania-A Geo-Additive Approach.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Karen P ChuStanford University Medical Center, Stanford, California 94305-5847, USA.
Sarah Shema
Simon Wu
Scarlett L Gomez
Ellen T Chang
Quynh-Thu Le
Stanford University · USCancer Prevention Institute of California · US

Funding

TUMOR HYPOXIA--MOLECULAR STUDIES &CLINICAL EXPLOITATIONP01CA067166 · NCI · STANFORD UNIVERSITY · PI DENKO, NICHOLAS C. · 1996 to 2017
$25.5M
Defining Molecular Markers for Tumor HypoxiaR01CA118582 · NCI · STANFORD UNIVERSITY · PI LE, QUYNH-THU XUAN · 2006 to 2010
$2.2M
NCI NIH HHS N01 PC035136NCI NIH HHS N02 PC015105NCI NIH HHS P01 CA067166NCI NIH HHS R01 CA118582
6 · The paper itself

Abstract

backgroundLower socioeconomic status (SES) has been linked to higher incidence of head and neck cancer (HNC) and lower survival. However, little is known about the effect of SES on HNC survival in Asians and Pacific Islanders (APIs). This study's purpose was to examine the effect of SES on disease-specific survival (DSS) and overall survival (OS) in APIs with HNC using population-based data.

methodsA total of 53,544 HNC patients (4,711 = APIs) were identified from the California Cancer Registry from 1988 to 2007. Neighborhood (block-group-level) SES, based on composite Census 1990 and 2000 data, was calculated for each patient based on address at diagnosis, categorized into statewide quintiles, and collapsed into 2 groups for comparison (low SES = quintiles 1-3; high SES = quintiles 4-5). DSS and OS were computed by the Kaplan-Meier method. Adjusted hazards ratios (HR) were estimated using Cox proportional hazards regression models.

resultsAmong APIs, lower neighborhood SES was significantly associated with poorer DSS (HR range for oral cavity, oropharynx, or larynx/hypopharynx cancer, 1.07-1.34) and OS (HR, 1.13-1.37) after adjusting for patient and tumor characteristics. Lower SES was significantly associated with poorer survival in API with all HNC sites combined: DSS HR: 1.26 (95% confidence interval [CI], 1.08-1.48) and OS HR, 1.30 (95% CI, 1.16-1.45).

conclusionsNeighborhood SES was associated with longer DSS and OS in API with HNC. The effect of SES on HNC survival should be considered in future studies, and particular attention should be paid to clinical care of lower-SES HNC patients.

Indexed as

Asian PeopleNative Hawaiian or Pacific IslanderSocial ClassAgedEthnicityFemaleHead and Neck NeoplasmsHealthcare DisparitiesHumansMaleMiddle Aged

Identifiers

PMID21509771
PMCPMC3117112
OpenAlexW2068535775

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.