ArticleThe ISME journal2011
Using experimental evolution to explore natural patterns between bacterial motility and resistance to bacteriophages.
Article in The ISME journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 31 citations in OpenAlex.
- Seed-Borne Bacterial Diversity of Fescue (Microorganisms · 2024Article
- Study on seed-borne cultivable bacterial diversity and antibiotic resistance ofFrontiers in microbiology · 2024Article
- Travelling with a parasite: the evolution of resistance and dispersal syndromes during experimental range expansion.Proceedings. Biological sciences · 2023Article
- Parallel evolution ofeLife · 2022Article
- Phage Reduce Stability for Regaining Infectivity during Antagonistic Coevolution with Host Bacterium.Viruses · 2019Article
- Bacteriophages ofViruses · 2018Review
- Genetics of dispersal.Biological reviews of the Cambridge Philosophical Society · 2018Review
- Predation in homogeneous and heterogeneous phage environments affects virulence determinants of Pseudomonas aeruginosa.Applied and environmental microbiology · 2013Article
- Genomes of surface isolates of Alteromonas macleodii: the life of a widespread marine opportunistic copiotroph.Scientific reports · 2012Article
- Polyclonality of concurrent natural populations of Alteromonas macleodii.Genome biology and evolution · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Resistance of bacteria to phages may be gained by alteration of surface proteins to which phages bind, a mechanism that is likely to be costly as these molecules typically have critical functions such as movement or nutrient uptake. To address this potential trade-off, we combine a systematic study of natural bacteria and phage populations with an experimental evolution approach. We compare motility, growth rate and susceptibility to local phages for 80 bacteria isolated from horse chestnut leaves and, contrary to expectation, find no negative association between resistance to phages and bacterial motility or growth rate. However, because correlational patterns (and their absence) are open to numerous interpretations, we test for any causal association between resistance to phages and bacterial motility using experimental evolution of a subset of bacteria in both the presence and absence of naturally associated phages. Again, we find no clear link between the acquisition of resistance and bacterial motility, suggesting that for these natural bacterial populations, phage-mediated selection is unlikely to shape bacterial motility, a key fitness trait for many bacteria in the phyllosphere. The agreement between the observed natural pattern and the experimental evolution results presented here demonstrates the power of this combined approach for testing evolutionary trade-offs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.