ReviewHuman vaccines2011
Human pathogenic hantaviruses and prevention of infection.
Review in Human vaccines, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 1 synthesis or guideline pooled it, 197 citations in OpenAlex.
- Land-cover, land-use and human hantavirus infection risk: a systematic review.Pathogens and global health · 2024Pooled it
- Cytokine Profiles and Antibody Response Associated to Choclo Orthohantavirus Infection.Frontiers in immunology · 2021Trial
- β2 integrin mediates hantavirus-induced release of neutrophil extracellular traps.The Journal of experimental medicine · 2014Trial
- Detection of Puumala hantavirus antigen in human intestine during acute hantavirus infection.PloS one · 2014Trial
- Soil-derived microbiota induces T regulatory cells and protect against mouse colitis, metabolic disease, and sepsis.Gut microbes · 2026Article
- Hantavirus seroprevalence and associated factors for exposure in south-central Uganda.Emerging microbes & infections · 2026Article
- Hantavirus on the rise: clinical, virological, immunological, and public health perspectives.Current opinion in immunology · 2026Review
- Global threats and regional trends: Navigating the complex landscape of human orthohantavirus infections.Infectious diseases & immunity · 2026Review
- Hantavirus Disease: A Comprehensive Narrative Review of Epidemiology, Pathogenesis, Diagnosis, and Treatment.Cureus · 2026Review
- Maternal antibody-mediated elimination of a Puumala hantavirus outbreak in a bank vole colony.PLoS pathogens · 2026Article
- Pathogenicity and virulence of Rodent-Borne Orthohantaviruses.Virulence · 2025Review
- Ebola Virus Disease: Uniquely Challenging Among the Viral Hemorrhagic Fevers.Open forum infectious diseases · 2025Review
- Aerostability of Sin Nombre Virus Aerosol Related to Near-Field Transmission.Pathogens (Basel, Switzerland) · 2025Article
- Recovering ImmunogenicVaccines · 2025Article
- A Multi-Valent Hantavirus Vaccine Based on Recombinant Modified Vaccinia Ankara Reduces Viral Load in a Mouse Infection Model.Vaccines · 2025Article
- Detection of Brno loanvirus (Loanvirus brunaense) in common noctule bats (Nyctalus noctula) in Southern Russia.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Review
- Identification and epidemiological analysis of a putative novel hantavirus in Australian flying foxes.Virus genes · 2025Article
- Rio Mamore Hantavirus Endemicity, Peruvian Amazon, 2020.Emerging infectious diseases · 2024Article
- Development and standardization of an enzyme-linked inmunosorbent for the detection of orthohantavirus infection in Argentina based on its bacterial-expressed nucleocapside protein.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hantaviruses are emerging viruses which are hosted by small mammals. When transmitted to humans, they can cause two clinical syndromes, hemorrhagic fever with renal syndrome or hantavirus cardiopulmonary syndrome. The review compiles the current list of hantaviruses which are thought to be pathogenic in humans on the basis of molecular or at least serological evidence. Whereas induction of a neutralizing humoral immune response is considered to be protective against infection, the dual role of cellular immunity (protection versus immunopathogenicity) is discussed. For active immunisation, inactivated virus vaccines are licensed in certain Asian countries. Moreover, several classical and molecular vaccine approaches are in pre-clinical stages of development. The development of hantavirus vaccines is hampered by the lack of adequate animal models of hantavirus-associated disease. In addition to active immunization strategies, the review summarizes other ways of infection prevention, as passive immunization, chemoprophylaxis, and exposition prophylaxis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.