ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2011
Power fluctuations in beta and gamma frequencies in rat globus pallidus: association with specific phases of slow oscillations and differential modulation by dopamine D1 and D2 receptors.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 38 citations in OpenAlex.
- Automatic sleep-wake classification and Parkinson's disease recognition using multifeature fusion with support vector machine.CNS neuroscience & therapeutics · 2024Article
- Synaptic Changes in Pallidostriatal Circuits Observed in the Parkinsonian Model Triggers Abnormal Beta Synchrony with Accurate Spatio-temporal Properties across the Basal Ganglia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Neural oscillatory activity and connectivity in children who stutter during a non-speech motor task.Journal of neurodevelopmental disorders · 2023Article
- Dopamine D4 Receptor Agonist Drastically Increases Delta Activity in the Thalamic Nucleus Reuniens: Potential Role in Communication between Prefrontal Cortex and Hippocampus.International journal of molecular sciences · 2023Article
- Translating Pathological Brain Activity Primers in Parkinson's Disease Research.Research (Washington, D.C.) · 2023Review
- Uncoupling the roles of firing rates and spike bursts in shaping the STN-GPe beta band oscillations.PLoS computational biology · 2020Article
- A biophysical model of striatal microcircuits suggests gamma and beta oscillations interleaved at delta/theta frequencies mediate periodicity in motor control.PLoS computational biology · 2020Article
- Interactions Between Motor Thalamic Field Potentials and Single-Unit Spiking Are Correlated With Behavior in Rats.Frontiers in neural circuits · 2020Article
- Low- and high-gamma oscillations deviate in opposite directions from zero-phase synchrony in the limbic corticostriatal loop.Journal of neurophysiology · 2016Article
- Globus Pallidus Externus Neurons Expressing parvalbumin Interconnect the Subthalamic Nucleus and Striatal Interneurons.PloS one · 2016Article
- Balancing the basal ganglia circuitry: a possible new role for dopamine D2 receptors in health and disease.Movement disorders : official journal of the Movement Disorder Society · 2015Article
- Altered resting-state EEG source functional connectivity in schizophrenia: the effect of illness duration.Frontiers in human neuroscience · 2015Article
- Corticostriatal coordination through coherent phase-amplitude coupling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Neurosystems: brain rhythms and cognitive processing.The European journal of neuroscience · 2014Review
- Alpha- and beta-band oscillations subserve different processes in reactive control of limb movements.Frontiers in behavioral neuroscience · 2014Article
- Diurnal influences on electrophysiological oscillations and coupling in the dorsal striatum and cerebellar cortex of the anesthetized rat.Frontiers in systems neuroscience · 2014Article
- Article
- Delta-mediated cross-frequency coupling organizes oscillatory activity across the rat cortico-basal ganglia network.Frontiers in neural circuits · 2013Article
- Altered pallido-pallidal synaptic transmission leads to aberrant firing of globus pallidus neurons in a rat model of Parkinson's disease.The Journal of physiology · 2012Article
- Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modulation of oscillatory activity through basal ganglia-cortical loops in specific frequency bands is thought to reflect specific functional states of neural networks. A specific negative correlation between beta and gamma sub-bands has been demonstrated in human basal ganglia and may be key for normal basal ganglia function. However, these studies were limited to Parkinson's disease patients. To confirm that this interaction is a feature of normal basal ganglia, we recorded local field potential (LFP) from electrodes in globus pallidus (GP) of intact rats. We found significant negative correlation between specific frequencies within gamma (≈ 60 Hz) and beta (≈ 14 Hz) bands. Furthermore, we show that fluctuations in power at these frequencies are differentially nested within slow (≈ 3 Hz) oscillations in the delta band, showing maximum power at distinct and different phases of delta. These results suggest a hierarchical organization of LFP frequencies in the rat GP, in which a low-frequency signal in the basal ganglia can predict the timing and interaction of power fluctuations across higher frequencies. Finally, we found that dopamine D(1) and D(2) receptor antagonists differentially affected power in gamma and beta bands and also had different effects on correlation between them and the nesting within delta, indicating an important role for endogenous dopamine acting on direct and indirect pathway neurons in the maintenance of the hierarchical organization of frequency bands. Disruption of this hierarchical organization and subsequent disordered beta-gamma balance in basal ganglia disorders such as Parkinson's disease may be important in the pathogenesis of their symptoms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.