Evidence map›Paper›PMID 21507234›Full record

ArticleBMC geriatrics2011

Analysis of frailty and survival from late middle age in the Beijing Longitudinal Study of Aging.

Jing Shi, Xiaowei Song, Pulin Yu, Zhe Tang, Arnold Mitnitski, Xianghua Fang, Kenneth Rockwood

Abstract readComparative Study
In one paragraph

Article in BMC geriatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  17. Characterization of the gut microbiota in frail elderly patients.Aging clinical and experimental research · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing ShiBeijing Institute of Geriatrics, Beijing Hospital, Ministry of Health, Beijing, China.
Xiaowei Song
Pulin Yu
Zhe Tang
Arnold Mitnitski
Xianghua Fang
Kenneth Rockwood

Funding

Canadian Institutes of Health Research MOP62823
6 · The paper itself

Abstract

backgroundFrailty in individuals can be operationalized as the accumulation of health deficits, for which several trends have been observed in Western countries. Less is known about deficit accumulation in China, the country with the world's largest number of older adults.

methodsThis study analyzed data from the Beijing Longitudinal Study of Aging, to evaluate the relationship between age and deficit accumulation in men and women and to evaluate the impact of frailty on mortality. Community dwelling people aged 55+ years at baseline (n = 3275) were followed every two to three years between 1992 and 2000, during which time 36% died. A Frailty Index was constructed using 35 deficits, drawn from a range of health problems, including symptoms, disabilities, disease, and psychological difficulties.

resultsMost deficits increased the eight-year risk of death and were more lethal in men than in women, although women had a higher mean level of frailty (Frailty Index = 0.11 ± 0.10 for men, 0.14 ± 0.12 for women). The Frailty Index increased exponentially with age, with a similar rate in men and women (0.038 vs. 0.039; r > 0.949, P < 0.01). A dose-response relationship was observed as frailty increased.

conclusionsA Frailty Index employed in a Chinese sample, showed properties comparable with Western data, but deficit accumulation appeared to be more lethal than in the West.

Indexed as

AgedAged, 80 and overAgingChinaCohort StudiesFemaleFollow-Up StudiesFrail ElderlyHumansLongitudinal StudiesMaleMiddle AgedResidence CharacteristicsStatistics as TopicSurvival Rate

Identifiers

PMID21507234
PMCPMC3239314

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.