ArticleVeterinary research2011
Chronic "Candidatus Mycoplasma turicensis" infection.
Article in Veterinary research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 32 citations in OpenAlex.
- Feline haemotropic Mycoplasma spp. in Portugal: association with identifiable risk factors, clinical parameters and prognostic factors.Companion animal health and genetics · 2026Article
- Haematology, serum biochemistry, innate and adaptive immune system responses to blood pathogen infections in cattle: A review.Parasitology research · 2026Review
- High prevalence of vector-borne protozoa and bacteria in dogs from Chad determined using a targeted next-generation sequencing approach.Scientific reports · 2025Article
- Molecular prevalence and phylogenetic analysis of hemotropic Mycoplasma species in cats in different regions of Iran.BMC microbiology · 2024Article
- Haemoplasma Prevalence and Diversity in Three InvasiveMicroorganisms · 2022Article
- Expanding the Universe of Hemoplasmas: Multi-Locus Sequencing Reveals Putative Novel Hemoplasmas in Lowland Tapirs (Microorganisms · 2022Article
- Haemoplasmosis in cats: European guidelines from the ABCD on prevention and management.Journal of feline medicine and surgery · 2018Article
- Infection with haemoplasma species in 22 cats with anaemia.Journal of feline medicine and surgery · 2016Article
- Lack of cross-protection against Mycoplasma haemofelis infection and signs of enhancement in "Candidatus Mycoplasma turicensis"-recovered cats.Veterinary research · 2015Article
- Hemotropic mycoplasmas in little brown bats (Myotis lucifugus).Parasites & vectors · 2014Article
- Prevalence and risk factor analysis of feline haemoplasma infection in New Zealand domestic cats using a real-time PCR assay.Journal of feline medicine and surgery · 2013Article
- GAPDH Pseudogenes and the Quantification of Feline Genomic DNA Equivalents.Molecular biology international · 2013Article
- Protection from reinfection in "Candidatus Mycoplasma turicensis"-infected cats and characterization of the immune response.Veterinary research · 2012Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
"Candidatus Mycoplasma turicensis" infects felids. The pathogenesis of "Candidatus M. turicensis" chronic infection is poorly understood. The goals of the present study were to (1) induce reactivation of the infection in chronic carrier cats by attempted immunosuppression, (2) identify potential tissue sequestration using real-time TaqMan® PCR and (3) monitor the humoral immune response by DnaK enzyme-linked immunosorbent assay (ELISA). Ten specified pathogen-free cats that had ostensibly recovered from experimental "Candidatus M. turicensis" infection were used: five cats (group 1) received high dose methylprednisolone (attempted immunosuppression), while five cats served as untreated controls (group 2). Besides weekly blood samples, tissue samples were collected from bone marrow, kidney, liver and salivary glands at selected time points. The cats in group 1 had significantly lower lymphocyte counts and higher blood glucose levels after methylprednisolone administration than the controls. After methylprednisolone administration one blood and three tissue samples from cats in group 1 tested PCR-positive; before the administration, only one sample was positive. All other samples tested PCR-negative. All cats stayed seropositive; the antibody levels of the cats in group 1 showed a significant transient decrease after methylprednisolone administration. This is the first study to report the presence of "Candidatus M. turicensis" in tissues of chronically infected cats and the persistence of anti-feline hemoplasma antibodies in the absence of detectable bacteremia. Methylprednisolone administration did not lead to a significant reactivation of the infection. Our results enhance the knowledge of "Candidatus M. turicensis" infection pathogenesis and are clinically relevant to the prognosis of hemoplasma-infected cats.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.