Evidence map›Paper›PMID 21506207›Full record

Trial reportDepression and anxiety2011

Potential impact of trauma on the ability to prevent depression among low-income mothers.

Michael Silverstein, Emily Feinberg, Howard Cabral, Yaminette Diaz Linhart, Jenna Sandler, Mark Hegel, Danielle Pierce Appugliese, William Beardslee

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Depression and anxiety, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Giving parents support: a randomized trial of peer support for parents after NICU discharge.Journal of perinatology : official journal of the California Perinatal Association · 2022
    Trial
  3. Trial
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Michael SilversteinBoston Medical Center, Boston, Massachusetts 02118, USA. michael. silverstein@bmc.org
Emily Feinberg
Howard Cabral
Yaminette Diaz Linhart
Jenna Sandler
Mark Hegel
Danielle Pierce Appugliese
William Beardslee
Boston University · USBoston Medical Center · USBoston Children's Hospital · USDartmouth College · US

Funding

Maternal Depression and Early Head StartK23MH074079 · NIMH · BOSTON MEDICAL CENTER · PI SILVERSTEIN, MICHAEL · 2006 to 2010
$875k
Pevention of Depression among Mothers of Young Children with Developmental DelayK23NR010588 · NINR · BOSTON MEDICAL CENTER · PI FEINBERG, EMILY · 2007 to 2009
$341k
Problem Solving Education Among Parents of Premature InfantsR03HD058075 · NICHD · BOSTON MEDICAL CENTER · PI SILVERSTEIN, MICHAEL · 2008 to 2009
$199k
NICHD NIH HHS R03 HD058075NICHD NIH HHS R03HD058075NIMH NIH HHS K23 MH074079NIMH NIH HHS K23MH074079NINR NIH HHS K23 NR010588NINR NIH HHS K23NR010588
6 · The paper itself

Abstract

backgroundViolent trauma is common in urban communities. We explored the hypothesis that past trauma could moderate the effect of a cognitive behavioral intervention designed to prevent depression among urban, low-income mothers.

methodsSynthesis of two pilot randomized trials of problem solving education (PSE) among 93 mothers of children hospitalized in the neonatal intensive care unit or enrolled in community-based Early Intervention programs. Outcomes included depressive symptoms, perceived stress, and social functioning. Results were adjusted for baseline depressive symptoms, then stratified according to subjects' trauma history.

resultsFifteen of the 44 PSE subjects (34%) experienced a moderately severe depressive symptom episode during the 3-month follow-up period, as opposed to 21 of 45 control subjects (47%), for a nearly significant adjusted odds ratio (aOR) of 0.36 (95% CI: 0.13, 1.02). Among mothers without trauma histories, far fewer PSE mothers (5 of 24; 21%) experienced an episode of moderately severe depressive symptoms than control mothers (12 of 26; 46%) for a significant aOR of 0.15 (95% CI: 0.03, 0.79). Conversely, among mothers with trauma histories, a similar proportion of PSE mothers (10 of 19; 53%) experienced an episode of moderately severe depressive symptoms as control mothers (9 of 19; 47%). Similar trends held for perceived stress and social functioning.

conclusionsPSE may be more effective at preventing depression among mothers without trauma histories. Our results are consistent with the depression treatment literature, but are novel because they support the principle of intervention moderation in risk prevention, as opposed to treatment, paradigm.

Indexed as

Life Change EventsPovertyProblem SolvingAdultChild, PreschoolCognitive Behavioral TherapyDepression, PostpartumDepressive DisorderDevelopmental DisabilitiesEarly Intervention, EducationalFeasibility StudiesFemaleFollow-Up StudiesHumansInfant, NewbornIntensive Care Units, Neonatal

Identifiers

PMID21506207
PMCPMC3110557
OpenAlexW2011457332

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.