Evidence map›Paper›PMID 21505557›Full record

ArticleCancer microenvironment : official journal of the International Cancer Microenvironment Society2010

Myeloid cells in cancer progression: unique subtypes and their roles in tumor growth, vascularity, and host immune suppression.

Pampee P Young, Shidrokh Ardestani, Bin Li

Open access · hybridAbstract read
In one paragraph

Article in Cancer microenvironment : official journal of the International Cancer Microenvironment Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Increased CD3Biology · 2021
    Article
  4. Article
  5. Article
  6. Tumor microenvironment and myeloid-derived suppressor cells.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2013
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Pampee P Young
Shidrokh Ardestani
Bin Li
Vanderbilt University · USVanderbilt University Medical Center · US

Funding

Immunobiology of Blood and Vascular Systems Training ProgramT32HL069765 · NHLBI · VANDERBILT UNIVERSITY · PI HAWIGER, JACK J · 2002 to 2016
$6.5M
Creating Super Stem Cells for Cardiac and Wound RepairR01HL088424 · NHLBI · VANDERBILT UNIVERSITY · PI YOUNG, PAMPEE P · 2008 to 2012
$1.9M
TNF-Mediated Tumor Promotion: The Role of Vascular LeukocytesI01BX000209 · VA · VETERANS HEALTH ADMINISTRATION · PI YOUNG, PAMPEE P · 2009 to 2011
–
BLRD VA I01 BX000209NHLBI NIH HHS R01 HL088424NHLBI NIH HHS T32 HL069765
6 · The paper itself

Abstract

Leukocytic infiltrates, particularly myeloid cells, can stimulate an anti-tumor immune response, but more often they stimulate tumor development, including promoting invasion, tumor growth, angiogenesis, and metastasis. Distinct myeloid phenotypes are being characterized that have been shown to promote tumor growth, angiogenesis, and metastasis. This review provides an overview of myeloid differentiation and spotlights specific pro-tumorogenic myeloid populations and their role in cancer progression. Efforts to characterize these pro-tumorogenic myeloid cell immunophenotypes may lead to novel targets for cancer therapy.

Indexed as

Myeloid derived suppressor cellsTie-2 expressing monocytesTumor associated macrophagesTumor microenvironmentVascular leukocytes

Identifiers

PMID21505557
PMCPMC3047625
OpenAlexW1982711335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.