Evidence map›Paper›PMID 21505140›Full record

ArticleJAMA2011

Whole-genome sequencing: a step closer to personalized medicine.

Boris Pasche, Devin Absher

Abstract readCommentEditorial
PubMed Publisher
In one paragraph

Article in JAMA, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Different perspectives on translational genomics in personalized medicineJournal of the Turkish German Gynecological Association · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. The cost of molecular-guided therapy in oncology: a prospective cost study alongside the MOSCATO trial.Genetics in medicine : official journal of the American College of Medical Genetics · 2017
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Boris Pasche
Devin Absher

Funding

Study of Lupus Vascular and Bone Longterm EndpointsP60AR048098 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DUNLOP, DOROTHY D. · 2002 to 2011
$11.4M
TGF-beta polymorphisms and breast cancer in familiesR01CA112520 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PASCHE, BORIS · 2005 to 2013
$2.1M
TGFBR1 Signaling in Colorectal CancerR01CA137000 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PASCHE, BORIS · 2010 to 2014
$1.5M
NCI NIH HHS R01 CA112520NCI NIH HHS R01 CA137000NIAMS NIH HHS 5P60AR048098
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genome, HumanSequence Analysis, DNAAdultAge of OnsetDecision MakingFemaleGenes, p53Genetic Predisposition to DiseaseHumansLeukemia, Myeloid, AcuteMedical OncologyPrecision MedicinePrognosis

Identifiers

PMID21505140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.