Evidence map›Paper›PMID 21505119›Full record

ReviewSchizophrenia bulletin2011

Transition to adulthood: the critical period for pre-emptive, disease-modifying care for schizophrenia and related disorders.

Patrick McGorry

Registry-linked trialAbstract readReview
In one paragraph

Review in Schizophrenia bulletin, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04249960 (Sustain and Reinforce the Transition From Child to Adult Mental Health Care in Switzerland), which is not on this map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04249960 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Sustain and Reinforce the Transition From Child to Adult Mental Health Care in Switzerland : A Monocentric Nested Cohort Randomized Controlled Trial: The SORT Study.

TypeinterventionalSponsorUniversity of Geneva, SwitzerlandRan2019 to 2022Enrolled200ConditionsPsychiatric Disorder, TransitionArmsManaged transition
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pathways to mental health services for young people: a systematic review.Social psychiatry and psychiatric epidemiology · 2018
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  8. Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs-cAMP Signaling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Patrick McGorryCentre for Youth Mental Health, Department of Psychiatry, University of Melbourne, Australia. pmcgorry@unimelb.edu.au

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an urgent need and a global opportunity to rethink not only the dominant research paradigms in etiological research but also to invest in less constrained strategies which cut across the existing diagnostic silos to seek out common risk factors, late as well as early neurodevelopmental processes, pathophysiologies, and novel treatment strategies. The high-quality research presented in this special issue of Schizophrenia Bulletin makes a compelling case for such a rethink. While there is still a genuine disconnect between our understanding of the complex and dramatic brain changes that occur during the transition to adulthood and the concurrent surge in incidence of mental ill-health, there is no doubt that a much more serious focus on the perionset stage of clinical disorders in young people with their rapidly evolving brains, social environments, and life trajectories could be extremely productive. Research access to these early stages of illness would be catalyzed by the widespread construction of engaging stigma-free portals and clinical scaffolding appropriate for young people in the 21st century. The latter are urgently required to supersede traditional models of care, which have served both patients and families so poorly, and equally have failed to unlock a deeper understanding of the origins and progression of potentially serious mental disorders.

Indexed as

Critical Period, PsychologicalHealth Services Needs and DemandMental Health ServicesSocial EnvironmentAdultAge FactorsBrainHumansMental DisordersRisk FactorsSchizophrenia

Identifiers

PMID21505119
PMCPMC3080696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.