ArticlePlant physiology2011
The role of PENNYWISE and POUND-FOOLISH in the maintenance of the shoot apical meristem in Arabidopsis.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 59 citations in OpenAlex.
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- Flower Development in Arabidopsis.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Chlorate-induced molecular floral transition revealed by transcriptomes.Open life sciences · 2023Article
- Genome-Wide Identification, Expression, and Interaction Analysis of BEL-Like Homeodomain Gene Family in Peach.Biochemical genetics · 2022Article
- Genome-wide characterization of the TALE homeodomain family and the KNOX-BLH interaction network in tomato.Plant molecular biology · 2022Article
- The Roles of BLH Transcription Factors in Plant Development and Environmental Response.International journal of molecular sciences · 2022Review
- The flowering transition pathways converge into a complex gene regulatory network that underlies the phase changes of the shoot apical meristem inFrontiers in plant science · 2022Article
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- Comparative transcriptome analyses define genes and gene modules differing between twoBiotechnology for biofuels · 2020Article
- Transcription Factor Networks in Leaves ofPlants (Basel, Switzerland) · 2019Article
- Clade I TGACG-Motif Binding Basic Leucine Zipper Transcription Factors Mediate BLADE-ON-PETIOLE-Dependent Regulation of Development.Plant physiology · 2019Article
- Duplication and Diversification ofFrontiers in plant science · 2018Article
- KNOTTED1 Cofactors, BLH12 and BLH14, Regulate Internode Patterning and Vein Anastomosis in Maize.The Plant cell · 2017Article
- Multiple Mobile mRNA Signals Regulate Tuber Development in Potato.Plants (Basel, Switzerland) · 2017Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Growth of the aerial part of the plant is dependent upon the maintenance of the shoot apical meristem (SAM). A balance between the self-renewing stem cells in the central zone (CZ) and organogenesis in the peripheral zone (PZ) is essential for the integrity, function, and maintenance of the SAM. Understanding how the SAM maintains a balance between stem cell perpetuation and organogenesis is a central question in plant biology. Two related BELL1-like homeodomain proteins, PENNYWISE (PNY) and POUND-FOOLISH (PNF), act to specify floral meristems during reproductive development. However, genetic studies also show that PNY and PNF regulate the maintenance of the SAM. To understand the role of PNY and PNF in meristem maintenance, the expression patterns for genes that specifically localize to the peripheral and central regions of the SAM were examined in Arabidopsis (Arabidopsis thaliana). Results from these experiments indicate that the integrity of the CZ is impaired in pny pnf plants, which alters the balance of stem cell renewal and organogenesis. As a result, pools of CZ cells may be allocated into initiating leaf primordia. Consistent with these results, the integrity of the central region of pny pnf SAMs can be partially restored by increasing the size of the CZ. Interestingly, flower specification is also reestablished by augmenting the size of the SAM in pny pnf plants. Taken together, we propose that PNY and PNF act to restrict organogenesis to the PZ by maintaining a boundary between the CZ and PZ.
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