Evidence map›Paper›PMID 21504208›Full record

ArticleOrganic letters2011

Regioselective hydroformylation of allylic alcohols.

Thomas E Lightburn, Omar A De Paolis, Ka H Cheng, Kian L Tan

Abstract read
In one paragraph

Article in Organic letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Distal-selective hydroformylation using scaffolding catalysis.Journal of the American Chemical Society · 2014
    Article
  3. Article
  4. Scaffolding Catalysis: Expanding the Repertoire of Bifunctional Catalysts.Synlett : accounts and rapid communications in synthetic organic chemistry · 2012
    Article
  5. Enantioselective hydroformylation of aniline derivatives.The Journal of organic chemistry · 2011
    Article
  6. Scaffolding catalysts: highly enantioselective desymmetrization reactions.Angewandte Chemie (International ed. in English) · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Thomas E LightburnBoston College, Merkert Chemistry Center, Chestnut Hill, Massachusetts 02467-3860, United States.
Omar A De Paolis
Ka H Cheng
Kian L Tan
Boston College · US

Funding

Practical Strategies for Controlling Selectivity in Organic ReactionsR01GM087581 · NIGMS · BOSTON COLLEGE · PI HOVEYDA, AMIR H · 2010 to 2013
$1.1M
NIGMS NIH HHS R01 GM087581NIGMS NIH HHS R01GM087581
6 · The paper itself

Abstract

A highly regioselective hydroformylation of allylic alcohols is reported toward the synthesis of β-hydroxy-acid and aldehyde products. The selectivity is achieved through the use of a ligand that reversibly binds to alcohols in situ, allowing for a directed hydroformylation to occur. The application to trisubstituted olefins was also demonstrated, which yields a single diastereomer product consistent with a stereospecific addition of CO and hydrogen.

Indexed as

AlcoholsAldehydesAlkenesCatalysisCombinatorial Chemistry TechniquesMolecular StructurePropanolsStereoisomerismAlcoholsAldehydesAlkenesallyl alcoholPropanols

Identifiers

PMID21504208
PMCPMC3096926
OpenAlexW1973109234

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.