Evidence map›Paper›PMID 21502584›Full record

ReviewCirculation2011

Pharmacogenomics: the genetics of variable drug responses.

Dan M Roden, Russell A Wilke, Heyo K Kroemer, C Michael Stein

Abstract readReview
In one paragraph

Review in Circulation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dan M RodenDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-0575, USA. dan.roden@vanderbilt.edu
Russell A Wilke
Heyo K Kroemer
C Michael Stein

Funding

PHARMACOGENOMICS OF ARRHYTHMIA THERAPYU01HL065962 · NHLBI · VANDERBILT UNIVERSITY · PI RODEN, DAN M · 2001 to 2009
$24.8M
Pharmacogenomics and Risk of Cardiovascular DiseaseU01HL069757 · NHLBI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI KRAUSS, RONALD M · 2001 to 2009
$24.7M
Pharmacogenomics of Arrhythmia TherapyU19HL065962 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RODEN, DAN M · 2010 to 2014
$17.4M
Pharmacogenomics and Risk of Cardiovascular DiseaseU19HL069757 · NHLBI · CHILDREN'S HOSPITAL & RES CTR AT OAKLAND · PI KRAUSS, RONALD M · 2010 to 2014
$12.8M
Pharmacogenetics of obesity and endocannabinergic modulation (POEM)R01DK080007 · NIDDK · VANDERBILT UNIVERSITY · PI WILKE, RUSSELL A. · 2009 to 2012
$1.2M
NHLBI NIH HHS U01 HL065962NHLBI NIH HHS U01 HL069757NHLBI NIH HHS U19 HL065962NHLBI NIH HHS U19 HL069757NIDDK NIH HHS R01 DK080007
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCardiovascular AgentsCardiovascular DiseasesGenetic VariationHumansPharmacogeneticsTreatment OutcomeCardiovascular Agents

Identifiers

PMID21502584
PMCPMC3093198

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.