Evidence map›Paper›PMID 21502563›Full record

ArticleHypertension (Dallas, Tex. : 1979)2011

New take on the role of angiotensin II in cardiac hypertrophy and fibrosis.

Mazen Kurdi, George W Booz

Abstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. 4-Hydroxychalcone attenuates AngII-induced cardiac remodeling and dysfunction via regulating PI3K/AKT pathway.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Zyxin protects from hypertension-induced cardiac dysfunction.Cellular and molecular life sciences : CMLS · 2022
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mazen KurdiDepartment of Chemistry and Biochemistry, Faculty of Sciences, Lebanese University, Rafic Hariri Educational Campus, Hadath, Lebanon.
George W Booz
Lebanese University · LB

Funding

Regulation of IL-6-Type Cytokine Cardioprotective Signaling in the Ischemic HeartR01HL088101 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI BOOZ, GEORGE W. · 2008 to 2012
$2.0M
NHLBI NIH HHS R01 HL088101NHLBI NIH HHS R01HL088101-02S1NHLBI NIH HHS R01HL088101-04
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AldosteroneAngiotensin IIAnimalsCardiomegalyFibrosisHumansHypertensionInflammationMiceMyocardiumOxidative StressReceptor, Angiotensin, Type 1SodiumVentricular RemodelingAldosteroneAngiotensin IIReceptor, Angiotensin, Type 1Sodium

Identifiers

PMID21502563
PMCPMC3098302
OpenAlexW1985905942

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.