ArticleThe Journal of physiology2011
Striatal cellular properties conserved from lampreys to mammals.
Article in The Journal of physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 72 citations in OpenAlex.
- Olfactory Projections to Locomotor Control Centers in the Sea Lamprey.International journal of molecular sciences · 2024Article
- The Basal Ganglia Downstream Control of Action - An Evolutionarily Conserved Strategy.Current neuropharmacology · 2024Review
- The neural bases of vertebrate motor behaviour through the lens of evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Dopamine Modulation ofFrontiers in physiology · 2022Article
- The Dopaminergic Control of Movement-Evolutionary Considerations.International journal of molecular sciences · 2021Review
- Action sequencing in the spontaneous swimming behavior of zebrafish larvae - implications for drug development.Scientific reports · 2017Article
- Current Opinions and Areas of Consensus on the Role of the Cerebellum in Dystonia.Cerebellum (London, England) · 2017Article
- Human-specific increase of dopaminergic innervation in a striatal region associated with speech and language: A comparative analysis of the primate basal ganglia.The Journal of comparative neurology · 2016Article
- Molecular and functional definition of the developing human striatum.Nature neuroscience · 2014Article
- GABAergic and glycinergic inputs modulate rhythmogenic mechanisms in the lamprey respiratory network.The Journal of physiology · 2014Article
- Liquid computing on and off the edge of chaos with a striatal microcircuit.Frontiers in computational neuroscience · 2014Article
- The evolutionary origin of the vertebrate basal ganglia and its role in action selection.The Journal of physiology · 2013Article
- Forebrain dopamine neurons project down to a brainstem region controlling locomotion.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Neuronal mechanisms of respiratory pattern generation are evolutionary conserved.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Dopamine differentially modulates the excitability of striatal neurons of the direct and indirect pathways in lamprey.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Evolutionarily conserved differences in pallial and thalamic short-term synaptic plasticity in striatum.The Journal of physiology · 2013Article
- The dopamine D2 receptor gene in lamprey, its expression in the striatum and cellular effects of D2 receptor activation.PloS one · 2012Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The striatum of the lamprey, the first vertebrate group to appear in evolution, shows striking similarities to that of mammals with respect to histochemical markers, afferent and efferent projections and the effect of dopamine depletion, which leads to hypokinetic motor symptoms. The cellular properties of lamprey striatal neurons were studied here using patch-clamp recordings in acute striatal slices. Sixty-five per cent of recorded neurons were characterised by a prominent inward rectification due to a K+ conductance of the Kir type. They had a ramping response with a long delay to the first action potential due to activation of a low-voltage-activated A-type K+ current. Many such inwardly rectifying neurons (IRNs) had a hyperpolarised resting membrane potential and some had spiny dendrites. The remaining 35% of the neurons (non-IRNs) represent a heterogeneous group, including some with characteristics similar to the fast-spiking interneuron of the mammalian striatum. They showed short-lasting, large after hyperpolarisations (AHPs) and discharged action potentials at high frequency. None of the recorded neurons were spontaneously active but they received GABAergic and glutamatergic synaptic input. The fact that most lamprey striatal neurons display inward rectification indicates that this is a conserved characteristic of striatal neurons throughout vertebrate phylogeny. This is a cellular property of critical importance for the operations of the striatum in mammals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.