ReviewThe Journal of physiology2011
Evaluating the adaptive-filter model of the cerebellum.
Review in The Journal of physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Review
- Cerebellar control of a unitary head direction sense.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Long-Term Synaptic Plasticity Tunes the Gain of Information Channels through the Cerebellum Granular Layer.Biomedicines · 2022Article
- A Liaison Brought to Light: Cerebellum-Hippocampus, Partners for Spatial Cognition.Cerebellum (London, England) · 2022Review
- Computational models of neurotransmission at cerebellar synapses unveil the impact on network computation.Frontiers in computational neuroscience · 2022Review
- Cerebellum as a kernel machine: A novel perspective on expansion recoding in granule cell layer.Frontiers in computational neuroscience · 2022Article
- Cellular-resolution mapping uncovers spatial adaptive filtering at the rat cerebellum input stage.Communications biology · 2020Article
- Parameter tuning differentiates granule cell subtypes enriching transmission properties at the cerebellum input stage.Communications biology · 2020Article
- Response Dynamics in an Olivocerebellar Spiking Neural Network With Non-linear Neuron Properties.Frontiers in computational neuroscience · 2019Article
- Computational Principles of Supervised Learning in the Cerebellum.Annual review of neuroscience · 2018Review
- Computational Theory Underlying Acute Vestibulo-ocular Reflex Motor Learning with Cerebellar Long-Term Depression and Long-Term Potentiation.Cerebellum (London, England) · 2017Article
- Inverse Stochastic Resonance in Cerebellar Purkinje Cells.PLoS computational biology · 2016Article
- Modeling the Cerebellar Microcircuit: New Strategies for a Long-Standing Issue.Frontiers in cellular neuroscience · 2016Review
- Redefining the cerebellar cortex as an assembly of non-uniform Purkinje cell microcircuits.Nature reviews. Neuroscience · 2015Review
- The 40-year history of modeling active dendrites in cerebellar Purkinje cells: emergence of the first single cell "community model".Frontiers in computational neuroscience · 2015Review
- Flocculus Purkinje cell signals in mouse Cacna1a calcium channel mutants of escalating severity: an investigation of the role of firing irregularity in ataxia.Journal of neurophysiology · 2014Article
- Normal motor adaptation in cervical dystonia: a fundamental cerebellar computation is intact.Cerebellum (London, England) · 2014Article
- An adaptive filter model of cerebellar zone C3 as a basis for safe limb control?The Journal of physiology · 2013Review
- Gating of long-term potentiation by nicotinic acetylcholine receptors at the cerebellum input stage.PloS one · 2013Article
- An internal model architecture for novelty detection: implications for cerebellar and collicular roles in sensory processing.PloS one · 2012Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The adaptive-filter model of the cerebellar microcircuit is in widespread use, combining as it does an explanation of key microcircuit features with well-specified computational power. Here we consider two methods for its evaluation. One is to test its predictions concerning relations between cerebellar inputs and outputs. Where the relevant experimental data are available, e.g. for the floccular role in image stabilization, the predictions appear to be upheld. However, for the majority of cerebellar microzones these data have yet to be obtained. The second method is to test model predictions about details of the microcircuit. We focus on features apparently incompatible with the model, in particular non-linear patterns in Purkinje cell simple-spike firing. Analysis of these patterns suggests the following three conclusions. (i) It is important to establish whether they can be observed during task-related behaviour. (ii) Highly non-linear models based on these patterns are unlikely to be universal, because they would be incompatible with the (approximately) linear nature of floccular function. (iii) The control tasks for which these models are computationally suited need to be identified. At present, therefore, the adaptive filter remains a candidate model of at least some cerebellar microzones, and its evaluation suggests promising lines for future enquiry.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.