Trial reportThe Journal of physiology2011
Specific modulation of corticospinal and spinal excitabilities during maximal voluntary isometric, shortening and lengthening contractions in synergist muscles.
Trial report in The Journal of physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
45 citing papers in PubMed, 113 citations in OpenAlex.
- Anodal tDCS improves neuromuscular adaptations to short-term resistance training of the knee extensors in healthy individuals.Journal of neurophysiology · 2024Trial
- Static stretch and dynamic muscle activity induce acute similar increase in corticospinal excitability.PloS one · 2020Trial
- Efficient and reliable characterization of the corticospinal system using transcranial magnetic stimulation.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2014Trial
- Eccentric training at long muscle lengths induces greater corticospinal and spinal reflex plasticity than eccentric training at short muscle lengths.Experimental physiology · 2025Article
- Corticomuscular coupling study for post-stroke rehabilitation: a scoping review.Journal of neuroengineering and rehabilitation · 2025Article
- Neuromuscular characteristics of eccentric, concentric and isometric contractions of the knee extensors.European journal of applied physiology · 2025Article
- Localized electrocortical activity as a function of single-leg squat phases and its relationship to knee frontal plane stability.Experimental brain research · 2024Article
- Gravity-efficient motor control is associated with contraction-dependent intracortical inhibition.iScience · 2023Article
- Regulation of primary afferent depolarization and homosynaptic post-activation depression during passive and active lengthening, shortening and isometric conditions.European journal of applied physiology · 2023Article
- Combined effect of contraction type and intensity on corticomuscular coherence during isokinetic plantar flexions.European journal of applied physiology · 2023Article
- Reliability of corticospinal excitability and intracortical inhibition in biceps femoris during different contraction modes.The European journal of neuroscience · 2023Article
- Enhanced corticospinal excitability in the tibialis anterior during static stretching of the soleus in young healthy individuals.PloS one · 2023Article
- Antagonist muscle torque at the ankle interfere with maximal voluntary contraction under isometric and anisometric conditions.Scientific reports · 2022Article
- Inter-Individual Variability in Motor Output Is Driven by Recruitment Gain in the Corticospinal Tract Rather Than Motor Threshold.Brain sciences · 2022Article
- Determining concentric and eccentric force-velocity profiles during squatting.European journal of applied physiology · 2022Article
- Corticospinal Excitability Is Lower During Eccentric Than Concentric Cycling in Men.Frontiers in physiology · 2022Article
- Intra-limb modulations of posterior root-muscle reflexes evoked from the lower-limb muscles during isometric voluntary contractions.Experimental brain research · 2021Article
- Specific modulation of corticomuscular coherence during submaximal voluntary isometric, shortening and lengthening contractions.Scientific reports · 2021Article
- Inter-muscle differences in modulation of motor evoked potentials and posterior root-muscle reflexes evoked from lower-limb muscles during agonist and antagonist muscle contractions.Experimental brain research · 2021Article
- Corticomuscular interactions during different movement periods in a multi-joint compound movement.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was designed to investigate the cortical and spinal mechanisms involved in the modulations of neural activation during lengthening compared with isometric and shortening maximal voluntary contractions (MVCs). Two muscles susceptible to different neural adjustments at the spinal level, the soleus (SOL) and medial gastrocnemius (MG), were compared. Twelve healthy males participated in at least two experimental sessions designed to assess corticospinal and spinal excitabilities. We compared the modulation of motor evoked potentials (MEPs) in response to transcranial magnetic stimulation and Hoffmann reflexes (H-reflexes) during isometric and anisometric MVCs. The H-reflex and MEP responses, recorded during lengthening and shortening MVCs, were compared with those obtained during isometric MVCs. The results indicate that the maximal amplitude of both MEP and H-reflex in the SOL were smaller (P < 0.01) during lengthening MVCs compared with isometric and shortening MVCs but similar (P > 0.05) in MG for all three muscle contraction types. The silent period that follows maximal MEPs was reduced (P < 0.01) during lengthening MVCs in the SOL but not the MG. Similar observations were obtained regardless of the initial length of the MG muscle. Collectively, the current results indicate that the relative contribution of both cortical and spinal mechanisms to the modulation of neural activation differs during lengthening MVCs and between two synergist muscles. The comparison of SOL and MG responses further suggests that the specific modulation of the corticospinal excitability during lengthening MVCs depends mainly on pre- and postsynaptic inhibitory mechanisms acting at the spinal level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.