Evidence map›Paper›PMID 21501825›Full record

ArticleCell host & microbe2011

XMRV as a human pathogen?

Mark A Wainberg, Kuan-Teh Jeang

Abstract read
In one paragraph

Article in Cell host & microbe, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mark A WainbergMcGill University AIDS Centre, Jewish General Hospital, Montreal, Quebec, Canada.
Kuan-Teh Jeang

Funding

Molecular Mechanisms Of Human Immunodeficiency Virus Trans-regulatory ProteinsZIAAI000547 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI JEANG, KUAN-TEH · 2009 to 2013
$5.9M
Mechanisms of Cellular Transformation by HTLV-1ZIAAI001023 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI JEANG, KUAN-TEH · 2009 to 2013
$4.2M
CIHRIntramural NIH HHS Z99 AI999999Intramural NIH HHS ZIA AI001023
6 · The paper itself

Abstract

Xenotropic murine leukemia virus-related virus (XMRV) has been proposed to be associated with prostate cancer and chronic fatigue syndrome (CFS). This proposition has been controversial because many investigators have failed to replicate the reported associations. Here, we explore whether XMRV is an authentic human pathogen in the light of recent findings that indicate otherwise.

Indexed as

DNA ContaminationDNA, ViralFatigue Syndrome, ChronicHumansMaleProstatic NeoplasmsReceptors, G-Protein-CoupledReceptors, VirusXenotropic and Polytropic Retrovirus ReceptorXenotropic murine leukemia virus-related virusDNA, ViralReceptors, G-Protein-CoupledReceptors, VirusXenotropic and Polytropic Retrovirus Receptor

Identifiers

PMID21501825
PMCPMC4551452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.