ArticleGynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology2011
Oocyte morphological abnormalities in overweight women undergoing in vitro fertilization cycles.
Article in Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03034941 (Short Term Weight Loss With Liraglutide and Metformin Before IVF in Infertile Obese PCOS Patients), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Short Term Weight Loss With Liraglutide and Metformin Before IVF in Infertile Obese PCOS Patients
Open the trial in the graphWho cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Human Oocyte Morphology and Outcomes of Infertility Treatment: a Systematic Review.Reproductive sciences (Thousand Oaks, Calif.) · 2022Pooled it
- When to test: defining the earliest reliable time for pregnancy detection and its prognostic value after frozen embryo transfer.AJOG global reports · 2026Article
- Obesity and overweight and associated factors among women with infertility undergoing assisted reproductive technology treatment in a low income setting.Scientific reports · 2025Article
- How to estimate the probability of a live birth after one or more complete IVF cycles? the development of a novel model in a single-center.BMC pregnancy and childbirth · 2025Article
- The impact of obesity on reproductive health and metabolism in reproductive-age females.Fertility and sterility · 2024Review
- Female BMI and Body Weight Is Not Associated with Oocyte Yield and Maturation in hCG, Agonist or Dual Trigger Cycles: A Large Observational Study including 5000 Cycles.Journal of clinical medicine · 2023Article
- Article
- Phenotyping ofBiomolecules · 2022Review
- Abnormal BMI in Male and/or Female Partners Are Deleterious for Embryonic Development and Pregnancy Outcome During ART Process: A Retrospective Study.Frontiers in endocrinology · 2022Article
- Cumulative Live Birth Rates According to Maternal Body Mass Index After First Ovarian Stimulation forFrontiers in endocrinology · 2020Article
- Effect of body mass index on pregnancy outcomes in a freeze-all policy: an analysis of 22,043 first autologous frozen-thawed embryo transfer cycles in China.BMC medicine · 2019 · on this mapArticle
- Association between parental anthropometric measures and the outcomes of intracytoplasmic sperm injection cycles.Journal of assisted reproduction and genetics · 2019Article
- Endogenous luteinizing hormone concentration and IVF outcome during ovarian stimulation in fixed versus flexible GnRH antagonist protocols: An RCT.International journal of reproductive biomedicine · 2018Article
- Obesity is not a descriptive factor for oxidative stress and viscosity in follicular fluid of in vitro fertilization patients.Irish journal of medical science · 2017Article
- The dangerous link between childhood and adulthood predictors of obesity and metabolic syndrome.Internal and emergency medicine · 2016Review
- Progressive obesity alters ovarian folliculogenesis with impacts on pro-inflammatory and steroidogenic signaling in female mice.Biology of reproduction · 2014Article
- Maternal obesity, infertility and mitochondrial dysfunction: potential mechanisms emerging from mouse model systems.Molecular human reproduction · 2013Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effect of elevated body mass index (BMI) on the oocyte quality was investigated in women undergoing in vitro fertilization (IVF) cycles. A total of 268 patients classified on the basis of BMI subject to the first reproductive treatment were included in this study: the normal weight (NW) group consisted of 160 patients with BMI 19-24.9 kg/m(2) and the overweight (OW) group consisted of 108 patients with BMI ≥ 25 kg/m(2). All women were treated with a standard long luteal protocol. The oocyte features were classified as extracytoplasmic or cytoplasmic abnormalities. Outcomes were oocyte morphology, embryo quality, fertilization and implantation rates, and the ovarian response to stimulation. A higher percentage of oocytes with granular cytoplasm was found in women with BMI ≥ 25 (p = 0.04). However, percentages of mature, immature oocytes and germinal vesicle were similar in both groups. No differences were found in fertilization and cleavage rates and percentages of embryo quality. The implantation rate (p < 0.001) was significantly lower in the OW group than in the NW group. The amount of gonadotrophins was significantly higher in OW group (p = 0.003). These findings suggest that the poor reproductive outcome of obese women is influenced by the release of ova with reduced fertilization potential.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.