Evidence map›Paper›PMID 21499959›Full record

ArticleEuropean radiology2011

Interactive magnetic resonance voiding cystourethrography (iMRVC) for vesicoureteric reflux (VUR) in unsedated infants: a feasibility study.

Owen J Arthurs, Andrea D Edwards, Ilse Joubert, Martin J Graves, Pat A K Set, David J Lomas

Abstract readEvaluation Study
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In one paragraph

Article in European radiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Diagnostic accuracy of magnetic resonance voiding cystourethrography for detecting vesico-ureteral reflux in children and adolescents.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
    Article
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Owen J ArthursDepartment of Radiology, Cambridge University Hospitals NHS Foundation Trust, Box 219, Addenbrookes Hospital, Hills Road, Cambridge, CB2 0QQ, UK.
Andrea D Edwards
Ilse Joubert
Martin J Graves
Pat A K Set
David J Lomas

Funding

Department of Health PB-PG-0807-14149Medical Research Council G0800411
6 · The paper itself

Abstract

objectivesThe current reference standard for diagnosing vesicoureteric reflux is the X-ray-based Micturating CystoUrethroGram (MCUG). The aim of this study was to evaluate the feasibility of performing interactive Magnetic Resonance voiding cysto-urethrography (iMRVC) in un-sedated infants.

methodsTwelve infants underwent conventional single-cycle MCUG followed by iMRVC. In iMRVC, patients were examined using an in-house developed fluoroscopic pulse sequence, which allows on-the-fly control of image contrast and geometry. A single acquisition was performed during bladder filling, during and after micturition, with interactive control over imaging parameters. Images were assessed for diagnostic quality and presence of VUR.

resultsEvery case of reflux identified with MCUG was identified on iMRVC (100% sensitivity). Over 24 renal units, there was 88% concordance (21/24) according to the presence of reflux between the two methods. There were three "false positives" detected by MRI, giving a specificity of 83.3%, PPV of 66.7% and NPV of 100%.

conclusioniMRVC is a feasible method for evaluating the renal tract in infants without the need for radiation or sedation. A formal evaluation is required to establish its diagnostic potential.

Indexed as

Cohort StudiesFeasibility StudiesFemaleHumansInfantInfant, NewbornMagnetic Resonance ImagingMaleProcedural SedationRadiography, InterventionalSensitivity and SpecificitySeverity of Illness IndexUrethraUrinary BladderUrinationVesico-Ureteral Reflux

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.