ArticlePediatric nephrology (Berlin, Germany)2011
Postnatal trends in creatinemia and its covariates in extremely low birth weight (ELBW) neonates.
Article in Pediatric nephrology (Berlin, Germany), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02147457 (Prematurity as Predictor of Children's Cardiovascular-renal Health), which is not on this map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prematurity as Predictor of Children's Cardiovascular-renal Health (PREMATCH)
Who cites it
24 citing papers in PubMed, 48 citations in OpenAlex.
- Evaluating renal function and age as predictors of amikacin clearance in neonates: model-based analysis and optimal dosing strategies.British journal of clinical pharmacology · 2016Trial
- Design and feasibility of "PREMATurity as predictor of children's Cardiovascular-renal Health" (PREMATCH): A pilot study.Blood pressure · 2015Trial
- Perinatal risk factors of renal outcome in former extremely low birth weight neonates.European journal of pediatrics · 2024Article
- Pharmacovigilance of nephrotoxic drugs in neonates: the Pottel method for acute kidney injury detection in ELBW neonates.Pediatric nephrology (Berlin, Germany) · 2024Article
- Perfused boundary region as biomarker for endothelial integrity in former preterms in adolescence.Pediatric research · 2023Article
- Characterizing dynamics of serum creatinine and creatinine clearance in extremely low birth weight neonates during the first 6 weeks of life.Pediatric nephrology (Berlin, Germany) · 2021Article
- Renal Precision Medicine in Neonates and Acute Kidney Injury: How to Convert a Cloud of Creatinine Observations to Support Clinical Decisions.Frontiers in pediatrics · 2020Review
- Creatinine Trends to Detect Ibuprofen-Related Maturational Adverse Drug Events in Neonatal Life: A Simulation Study for the ELBW Newborn.Frontiers in pharmacology · 2020Article
- The use of PBPK modeling across the pediatric age range using propofol as a case.Journal of pharmacokinetics and pharmacodynamics · 2018Article
- Article
- Dose-Finding Study of Omeprazole on Gastric pH in Neonates with Gastro-Esophageal Acid Reflux Using a Bayesian Sequential Approach.PloS one · 2016Article
- Pharmacokinetics in neonatal prescribing: evidence base, paradigms and the future.British journal of clinical pharmacology · 2015Review
- Retinopathy of Prematurity among Very-Low-Birth-Weight Infants in Korea: Incidence, Treatment, and Risk Factors.Journal of Korean medical science · 2015Article
- Adverse drug reactions in neonates and infants: a population-tailored approach is needed.British journal of clinical pharmacology · 2015Article
- Serum creatinine concentration in very-low-birth-weight infants from birth to 34-36 wk postmenstrual age.Pediatric research · 2015Article
- Recognition and reporting of AKI in very low birth weight infants.Clinical journal of the American Society of Nephrology : CJASN · 2014Article
- The interplay between drugs and the kidney in premature neonates.Pediatric nephrology (Berlin, Germany) · 2014Review
- A neonatal amikacin covariate model can be used to predict ontogeny of other drugs eliminated through glomerular filtration in neonates.Pharmaceutical research · 2014Article
- Chronic inhibition of cGMP-specific phosphodiesterase 5 suppresses endoplasmic reticulum stress in heart failure.British journal of pharmacology · 2013Article
- Clinical pharmacology of indomethacin in preterm infants: implications in patent ductus arteriosus closure.Paediatric drugs · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To document trends and covariates of creatinemia (Scr) in extremely low birth weight (ELBW, < 1,000 g) neonates, maternal characteristics [betamethasone, premature preterm rupture of membranes (PPROM), pre-eclampsia, maternal Scr], characteristics at delivery [gestational age (GA), birth weight (BW), small for GA (SGA), Apgar, intubation] and during neonatal stay [ventilation, oxygen, parenteral nutrition, ibuprofen, steroids, intraventricular hemorrhage, retinopathy of prematurity (ROP), phototherapy] were linked with Scr observations. Data were reported by median and range or incidence. Characteristics in ELBW neonates with raised peak Scr (>P75) were compared to controls (<P75). In 151 ELBW neonates, an initial increase in Scr was observed, resulting in a peak Scr on day 3 or 4 of 99.9 (46.8-221.8) μmol/l with subsequent decrease. In cases (n = 37) with a peak Scr >P75 (112.3 μmol/l), Scr remained elevated until day 28. Mothers of cases received less betamethasone, neonates had a lower GA, lower BW, lower Apgar, and needed more often intubation. Postnatal ventilation, oxygen, parenteral nutrition, ibuprofen, steroids, ROP, and intraventricular hemorrhage were different. GA and ventilation or Apgar were independent factors for raised peak Scr. ELBW neonates display trends similar to heavier neonates, but peak Scr is higher, and the subsequent decrease slower. Raised creatinemia in ELBW neonates reflects immaturity (GA) and morbidity (ventilation, Apgar).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.