ArticleMedical oncology (Northwood, London, England)2012
Absence of human papillomavirus in patients with breast cancer in north-west China.
Article in Medical oncology (Northwood, London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- An updated systemic review and meta-analysis on human papillomavirus in breast carcinogenesis.Frontiers in oncology · 2023Pooled it
- HPV-driven breast carcinogenesis: associations with tumor severity, Ki67 expression and metastasis.Infectious agents and cancer · 2025Article
- Human Cytomegalovirus Infection and Breast Cancer: A Literature Review of Clinical and Experimental Data.Biology · 2025Review
- Detection ofInfection and drug resistance · 2025Article
- The Role of Oncogenic Viruses in the Pathogenesis of Sporadic Breast Cancer: A Comprehensive Review of the Current Literature.Pathogens (Basel, Switzerland) · 2024Review
- Human papillomaviruses and breast cancer: A systematic review and meta‑analysis.Oncology letters · 2024Article
- High rate of high-risk human papillomavirus among benign and breast cancer patients in Ethiopia.PloS one · 2024Article
- High Frequency of Epstein-Barr Virus and Absence of Papillomavirus in Breast Cancer Patients from Brazilian Northeast.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Human Papillomavirus in Breast Carcinogenesis: A Passenger, a Cofactor, or a Causal Agent?Biology · 2021Review
- Presence of HPV, EBV and HMTV Viruses Among Egyptian Breast Cancer Women: Molecular Detection and Clinical Relevance.Infection and drug resistance · 2021Article
- Human papilloma virus (HPV) profiles in breast cancer: future management.Annals of translational medicine · 2020Review
- Human papillomavirus infection increases the risk of breast carcinoma: a large-scale systemic review and meta-analysis of case-control studies.Gland surgery · 2019Article
- Low Prevalence of Human Papilloma Virus in Patients with Breast Cancer, Kerman; IranAsian Pacific journal of cancer prevention : APJCP · 2018Article
- Oncogenic Viruses and Breast Cancer: Mouse Mammary Tumor Virus (MMTV), Bovine Leukemia Virus (BLV), Human Papilloma Virus (HPV), and Epstein-Barr Virus (EBV).Frontiers in oncology · 2018Review
- Detection of Human Papillomavirus in Korean Breast Cancer Patients by Real-Time Polymerase Chain Reaction and Meta-Analysis of Human Papillomavirus and Breast Cancer.Journal of pathology and translational medicine · 2016Article
- No Significant Association between Human Papillomavirus and Breast Cancer, Sanandaj, IranAsian Pacific journal of cancer prevention : APJCP · 2016Article
- Human papillomavirus infection and risk of breast cancer: a meta-analysis of case-control studies.Infectious agents and cancer · 2016Article
- Human Papilloma Viruses and Breast Cancer - Assessment of Causality.Frontiers in oncology · 2016Review
- Inconclusive role of human papillomavirus infection in breast cancer.Infectious agents and cancer · 2015Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to investigate the human papillomavirus (HPV) infection rate in malignant and benign breast tumours in north-west Chinese patients. Unselected fresh tissue samples were extracted from 48 invasive breast carcinoma and 30 benign breast tumours between August 2009 and August 2010. We used real-time fluorescence quantitative PCR (FQ-PCR) and in situ hybridization to detect HPV 6, 11 and 16, 18 sequences targeting the E6, E7 open-reading frame. The presence of HPV 6, 11 was only demonstrated in the 3 (10%) benign phyllodes tumour specimens. No HPV infection was detected in all the 48 invasive breast carcinoma. Specifically, all the positive specimens were detected by in situ hybridization but not in FQ-PCR. In addition, we found that the positive specimens became negative after 3 months frozen at -70°C. HPV was absent in patients with breast tumours in north-west China.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.