ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2012
Undertreatment of osteoporosis in persons with dementia? A population-based study.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Alzheimer's disease and its associated risk of bone fractures: a narrative review.Frontiers in endocrinology · 2023Pooled it
- Inappropriate Drug Use in People with Cognitive Impairment and Dementia: A Systematic Review.Current clinical pharmacology · 2015Pooled it
- Fracture prevention in patients with cognitive impairment presenting with a hip fracture: secondary analysis of data from the HORIZON Recurrent Fracture Trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014Trial
- Dementia and the Impact of Acetylcholinesterase Inhibitors on Falls, Fractures and Mortality in a Geriatric Cohort: A 4-Year Follow-Up Study.Journal of clinical medicine · 2026Article
- Mental disorders and osteoporosis treatment in patients with hip fracture-a Danish population-based cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Time to reframe osteoporosis: a position statement to characterize the osteoporosis care gap.JBMR plus · 2026Review
- Scoping review exploring the impact of hip fracture in older adults with cognitive impairment or dementia.BMJ open · 2025Article
- Analysis of Preventive Effect of Bisphosphonate for Osteoporotic Fracture in Patients with Alzheimer's Disease and Patient Mortality.Journal of clinical medicine · 2025Article
- Osteoporosis as a Potential Modifiable Risk Factor for Dementia in Thailand: A Cross-Sectional Analysis.Cureus · 2024Article
- Effects of risk factors on the development and mortality of early- and late-onset dementia: an 11-year longitudinal nationwide population-based cohort study in South Korea.Alzheimer's research & therapy · 2024Article
- Association between cognitive function and body composition in older adults: data from NHANES (1999-2002).Frontiers in aging neuroscience · 2024Article
- Prevalence and general characteristics of dementia: a nationwide population-based study of electronic health records in Türkiye.Turkish journal of medical sciences · 2024Article
- Effects ofJournal of public health in Africa · 2023Article
- The association between multimorbidity and osteoporosis investigation and treatment in high-risk fracture patients in Australia: A prospective cohort study.PLoS medicine · 2023Article
- The Impact of Frailty, Falls and Cognition on Osteoporosis Management in the Oldest Old.Calcified tissue international · 2022Article
- Osteoporosis and Dementia: Establishing a Link.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021Article
- Bone and Lean Mass Loss and Cognitive Impairment for Healthy Elder Adults: Analysis of the Nutrition and Health Survey in Taiwan 2013-2016 and a Validation Study With Structural Equation Modeling.Frontiers in nutrition · 2021Article
- Are Nursing Home Residents With Dementia Appropriately Treated for Fracture Prevention?Journal of the American Medical Directors Association · 2021Article
- Sex Differences in Associations of Cognitive Function with Perceptions of Pain in Older Adults.Journal of Alzheimer's disease : JAD · 2019Article
- A comprehensive overview on osteoporosis and its risk factors.Therapeutics and clinical risk management · 2018Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledIn this population-based study of more than 2,600 elderly, people with dementia received less preventive treatment for osteoporosis compared to people without dementia, although osteoporotic fractures were more common in patients with dementia. Thus, our results indicate an undertreatment of osteoporosis in dementia.
introductionThis study compares the use of osteoporosis drugs in elderly with and without dementia, taking into account osteoporotic fractures and type of housing.
methodsWe analyzed data from the baseline examination (2001-2004) of The Swedish National Study on Aging and Care- Kungsholmen (SNAC-K), Stockholm, Sweden. Participants were aged ≥ 66 years (n = 2610). We analysed the use of bisphosphonates, raloxifene, and calcium/vitamin D combinations in relation to clinically based dementia diagnosis. Information about osteoporotic fractures during the previous 4 years was obtained from the Swedish National Patient Register. We used logistic regression to analyze the association between dementia status and use of osteoporosis drugs.
resultsOsteoporosis drugs (mainly calcium/vitamin D combinations) were used by 5% of the persons with dementia and 12% of the persons without dementia. Furthermore, 25% of the persons with dementia and 7% of the persons without dementia had had at least one osteoporotic fracture during the past 4 years. After controlling for age, sex, osteoporotic fractures, and type of housing (own home or institution), persons with dementia were less likely to use osteoporosis drugs than persons without dementia (OR = 0.34; 95% CI, 0.19-0.59).
conclusionsOur results indicate an undertreatment of osteoporosis in persons with dementia, although osteoporotic fractures are common among these patients.
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