Evidence map›Paper›PMID 21499597›Full record

ArticleCanadian respiratory journal

A decade of respiratory syncytial virus epidemiology and prophylaxis: translating evidence into everyday clinical practice.

Bosco A Paes, Ian Mitchell, Anna Banerji, Krista L Lanctôt, Joanne M Langley

Open access · goldAbstract readCase Reports
In one paragraph

Article in Canadian respiratory journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.

  1. Pooled it
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  8. Estimating the Incidence of First RSV Hospitalization in Children Born in Ontario, Canada.Journal of the Pediatric Infectious Diseases Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Bosco A PaesDepartment of Pediatrics, McMaster University, Hamilton, Ontario. paes@mcmaster.ca
Ian Mitchell
Anna Banerji
Krista L Lanctôt
Joanne M Langley
Alberta Children's Hospital · CAIzaak Walton Killam Health Centre · CAMcMaster University · CASt. Michael's Hospital · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) is a common infection in infancy, with nearly all children affected by two years of age. Approximately 0.5% to 2.0% of all children are hospitalized with lower respiratory tract disease, of which 50% to 90% have bronchiolitis and 5% to 40% have pneumonia. Morbidity and mortality are highest in children with nosocomial infection and in those with underlying medical illnesses such as cardiac and chronic lung disease. Aboriginal children residing in remote northern regions are specifically considered to be at high risk for hospitalization due to RSV infection. Thorough hand washing and health education are the principal strategies in primary prevention. In the absence of a vaccine, palivizumab prophylaxis is currently the best intervention to reduce the burden of illness and RSV-related hospitalization in high-risk children. Health care professionals should provide palivizumab prophylaxis cost effectively in accordance with recommendations issued by pediatric societies and national advisory bodies. The present article reviews the epidemiology of RSV infection and the short- and long-term impact of disease in high-risk infants and special populations. Prevention strategies and treatment are discussed based on the existing scientific evidence, and future challenges in the management of RSV infection are addressed.

Indexed as

Respiratory Syncytial VirusesAdultAntibodies, Monoclonal, HumanizedAntiviral AgentsChildChild, PreschoolCross InfectionEvidence-Based MedicineFemaleHumansInfantPalivizumabPregnancyRespiratory Syncytial Virus InfectionsRisk FactorsAntibodies, Monoclonal, HumanizedAntiviral AgentsmotavizumabPalivizumab

Identifiers

PMID21499597
PMCPMC3084427
OpenAlexW85114486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.