Evidence map›Paper›PMID 21499552›Full record

ArticleHarmful algae2011

Aerosolized Red Tide Toxins (Brevetoxins) and Asthma: Continued health effects after 1 hour beach exposure.

Barbara Kirkpatrick, Lora E Fleming, Judy A Bean, Kate Nierenberg, Lorraine C Backer, Yung Sung Cheng, Richard Pierce, Andrew Reich, Jerome Naar, Adam Wanner and 4 more

Abstract read
In one paragraph

Article in Harmful algae, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Emerging Insights into Brevetoxicosis in Sea Turtles.Animals : an open access journal from MDPI · 2024
    Review
  5. Review
  6. Article
  7. Detection of Brevetoxin in Human Plasma by ELISA.Journal of analytical toxicology · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Harmful algae · 2012
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Barbara KirkpatrickMote Marine Laboratory, Sarasota, Florida, 34236.
Lora E Fleming
Judy A Bean
Kate Nierenberg
Lorraine C Backer
Yung Sung Cheng
Richard Pierce
Andrew Reich
Jerome Naar
Adam Wanner
William M Abraham
Yue Zhou
Julie Hollenbeck
Daniel G Baden

Funding

The Respiratory Eff. Study of Aerosolized Red Tide Toxins in HumansP01ES010594 · NIEHS · UNIVERSITY OF NORTH CAROLINA WILMINGTON · PI BADEN, DANIEL G · 2000 to 2011
$15.2M
Toxic Harmful Algal Blooms (HABs)P50ES012736 · NIEHS · UNIVERSITY OF MIAMI ROSENTEIL SCHOOL · PI FLEMING, LORA ELDERKIN · 2004 to 2010
$2.7M
NIEHS NIH HHS P01 ES010594NIEHS NIH HHS P50 ES012736
6 · The paper itself

Abstract

Blooms of the toxic dinoflagellate, Karenia brevis, produce potent neurotoxins in marine aerosols. Recent studies have demonstrated acute changes in both symptoms and pulmonary function in asthmatics after only 1 hour of beach exposure to these aerosols. This study investigated if there were latent and/or sustained effects in asthmatics in the days following the initial beach exposure during periods with and without an active Florida red tide.Symptom data and spirometry data were collected before and after 1 hour of beach exposure. Subjects kept daily symptom diaries and measured their peak flow each morning for 5 days following beach exposure. During non-exposure periods, there were no significant changes in symptoms or pulmonary function either acutely or over 5 days of follow-up. After the beach exposure during an active Florida red tide, subjects had elevated mean symptoms which did not return to the pre-exposure baseline for at least 4 days. The peak flow measurements decreased after the initial beach exposure, decreased further within 24 hours, and continued to be suppressed even after 5 days. Asthmatics may continue to have increased symptoms and delayed respiratory function suppression for several days after 1 hour of exposure to the Florida red tide toxin aerosols.

Identifiers

PMID21499552
PMCPMC3076944

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.