Evidence map›Paper›PMID 21497753›Full record

ArticleDevelopmental cell2011

LUMENating blood vessels.

M Luisa Iruela-Arispe

Abstract readComment
In one paragraph

Article in Developmental cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

M Luisa Iruela-ArispeDepartment of Molecular, Cell, and Developmental Biology, UCLA, Los Angeles, CA 90095, USA. arispe@mcdb.ucla.edu

Funding

Notch Signaling in Vascular Development and HomeostasisR01HL085618 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRUELA-ARISPE, M. LUISA · 2007 to 2011
$1.9M
NHLBI NIH HHS R01 HL085618
6 · The paper itself

Abstract

The acquisition of a lumen is an essential step in vascular morphogenesis. In this issue of Developmental Cell, Xu et al. (2011) show that the small GTPase Rasip is a critical regulator of cytoskeleton dynamics and cell adhesion, which together drive the emergence of vascular lumens.

Identifiers

PMID21497753
PMCPMC3099250

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.