Evidence map›Paper›PMID 21497553›Full record

ReviewTrends in parasitology2011

The emerging world of small silencing RNAs in protozoan parasites.

Vanessa D Atayde, Christian Tschudi, Elisabetta Ullu

Abstract readReview
In one paragraph

Review in Trends in parasitology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vanessa D AtaydeDepartment of Internal Medicine, School of Medicine, Yale University, New Haven, CT 06536, USA.
Christian Tschudi
Elisabetta Ullu

Funding

TRANSCRIPTION AND RNA PROCESSING IN TRYPANOSOMESR01AI028798 · NIAID · YALE UNIVERSITY · PI TSCHUDI, CHRISTIAN · 1990 to 2020
$10.9M
SMALL RNAS AND THEIR ROLE IN TRYPANOSOME BIOLOGYR01AI056333 · NIAID · YALE UNIVERSITY · PI ULLU, ELISABETTA · 2003 to 2012
$3.3M
RNA METABOLISM IN TRYPANOSOMESR37AI028798 · NIAID · YALE UNIVERSITY · PI ULLU, ELISABETTA · 2010 to 2013
$2.9M
NIAID NIH HHS AI28798NIAID NIH HHS AI56333NIAID NIH HHS R01 AI028798NIAID NIH HHS R01 AI056333NIAID NIH HHS R37 AI028798
6 · The paper itself

Abstract

A new RNA world has emerged in the past 10 years with the discovery of a plethora of 20- to 30-nucleotide long small RNAs that are involved in various gene silencing mechanisms. These small RNAs have considerably changed our view of the regulation of gene expression in eukaryotic organisms, with a major shift towards epigenetic and post-transcriptional mechanisms. In this article, we focus on the striking diversity of small silencing RNAs that have been identified in several protozoan parasites and their potential biological role.

Indexed as

AnimalsEukaryotaGene SilencingRNA, Small InterferingRNA, Small Interfering

Identifiers

PMID21497553
PMCPMC3124596

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.