Evidence map›Paper›PMID 21495079›Full record

Trial reportInternational journal of geriatric psychiatry2011

Long-term effectiveness of collaborative depression care in older primary care patients with and without PTSD symptoms.

Domin Chan, Ming-Yu Fan, Jürgen Unützer

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in International journal of geriatric psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012
    Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Trauma and posttraumatic stress disorder in older adults.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Domin ChanUniversity of Washington School of Social Work, Seattle, USA. dominc@uw.edu
Ming-Yu Fan
Jürgen Unützer

Funding

Training Geriatric Mental Health Services ResearchersT32MH073553 · NIMH · DARTMOUTH-HITCHCOCK CLINIC · PI BRUCE, MARTHA L · 2005 to 2019
$6.4M
NIMH NIH HHS T32 MH073553
6 · The paper itself

Abstract

objectiveDepressed patients with comorbid post-traumatic stress disorder (PTSD) are more functionally impaired and may take longer to respond to depression treatment than patients without PTSD. This study examined the long-term effects of PTSD on depression severity, treatment response, and health care costs among older adults.

methodsPatients were recruited from 18 primary care clinics in five states. A total of 1801 patients aged 60 years or older with major depression or dysthymia were randomized to Improving Mood Promoting Access to Collaborative Treatment (IMPACT) collaborative care or usual care. The study included 191 (10.6%) subjects who screened positive for PTSD. Depression severity, assessed by the Hopkins Depression Symptom Checklist, was used to estimate depression-free days (DFDs) over 24 months. Total health care costs included inpatient, outpatient, and pharmacy costs.

resultsDepressed patients with PTSD had higher depression severity than patients without PTSD symptoms at baseline. Over 2 years, intervention patients with PTSD symptoms had relatively the same benefits from collaborative care (99 more DFDs than usual care patients) as patients without PTSD (108 more DFDs than usual care) (p = 0.85). Total health care costs did not differ significantly for depressed patients with and without PTSD symptoms.

conclusionDepressed older adults with PTSD symptoms were more depressed at baseline, but collaborative care (compared to usual care) produced similar improvements in depression severity in both groups. This reduction of depression symptoms was observed for up to 12 months after the intervention ended, suggesting that long-term improvements in depression are possible with collaborative care in patients with and without PTSD symptoms.

Indexed as

Cooperative BehaviorAgedAnalysis of VarianceDepressive DisorderDysthymic DisorderFemaleHealth Care CostsHealth Services for the AgedHumansMaleMental Health ServicesPrimary Health CarePsychiatric Status Rating ScalesPsychotherapy, BriefStress Disorders, Post-Traumatic

Identifiers

PMID21495079
PMCPMC3998660

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.