ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2011
MRI findings in children with tuberculous meningitis: a comparison of HIV-infected and non-infected patients.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- A systemic review of tuberculosis with HIV coinfection in children.Pediatric radiology · 2017Pooled it
- Incidence of multidrug-resistant tuberculosis disease in children: systematic review and global estimates.Lancet (London, England) · 2014Pooled it
- Cryptococcosis in Pediatric Renal Transplant Recipients: Comparative Insights from Adult Cases.Medicina (Kaunas, Lithuania) · 2025Review
- Tuberculous Meningitis Across the Lifespan.The Journal of infectious diseases · 2025Review
- Tuberculosis revisted: classic imaging findings in childhood.Pediatric radiology · 2023Review
- Strengthening Tuberculosis Services for Children and Adolescents in Low Endemic Settings.Pathogens (Basel, Switzerland) · 2022Article
- Tuberculous meningitis in children: Clinical management & outcome.The Indian journal of medical research · 2019Review
- Human immunodeficiency virus-related cerebral white matter disease in children.Pediatric radiology · 2019Review
- Recent Developments in Tuberculous Meningitis Pathogenesis and Diagnostics.Wellcome open research · 2019Review
- Imaging Features of the Brain, Cerebral Vessels and Spine in Pediatric Tuberculous Meningitis With Associated Hydrocephalus.The Pediatric infectious disease journal · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRadiological studies on HIV infection in tuberculous meningitis (TBM) in children are limited to small, retrospective studies using CT features. They report that HIV-infected children are less likely to display meningovascular enhancement, tuberculoma formation and obstructive hydrocephalus. No similar MRI-based studies were found in the literature. PURPOSE: The purpose of this study is to compare the MRI features of TBM in HIV-infected and uninfected children.
methodsRetrospective descriptive study comparing clinical, laboratory and MRI features of 8 HIV-infected and 19 HIV-uninfected children with TBM.
resultsIntense basal meningeal enhancement occurred less frequently (p = 0.31) in HIV-infected children whilst cerebral atrophy was more commonly encountered (p = 0.06) Neither finding was however of statistical significance. All HIV-infected children had visible meningeal nodules on MR imaging compared to 72% in HIV-uninfected children with TBM. No differences were noted regarding number or location of infarcts and presence of hydrocephalus. Hydrocephalus in HIV-infected children was exclusively of communicating nature.
conclusionsThe MRI criteria for diagnosis of TBM apply to HIV-infected children. The presence of nodular meningeal disease in all HIV-infected children has not previously been reported and requires further investigation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.