ArticleJournal of physical organic chemistry2010
An Analysis of All the Relevant Facts and Arguments Indicates that Enzyme Catalysis Does Not Involve Large Contributions from Nuclear Tunneling.
Article in Journal of physical organic chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Donor-Acceptor Separation Augments Temperature Dependence of Kinetic Isotope Effects in NADH Model Hydride Transfer Reactions: Mimicking Enzyme versus Mutant Dynamics.The journal of physical chemistry. B · 2026Article
- Free energy relationship analysis for temperature dependence of hydride kinetic isotope effects of NADH/NADChemical science · 2026Article
- How important are quantum mechanical effects in controlling biological functions: Enzymes, electron transfer and bird navigation.Protein science : a publication of the Protein Society · 2026Review
- Large Temperature Dependence of Large Kinetic Isotope Effects of Multistep Hydride Reduction ofThe Journal of organic chemistry · 2025Article
- Rigidity Analysis of Hydride Tunneling Ready States from Secondary Kinetic Isotope Effects and Hammett Correlations: Relating to the Temperature Dependence of Kinetic Isotope Effects.Journal of physical organic chemistry · 2025Article
- Interplay of structural preorganization and conformational sampling in UDP-glucuronic acid 4-epimerase catalysis.Nature communications · 2024Article
- Correlation of temperature dependence of hydride kinetic isotope effects with donor-acceptor distances in two solvents of different polarities.Organic & biomolecular chemistry · 2023Article
- Quantifying the limits of transition state theory in enzymatic catalysis.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Perspective: Defining and quantifying the role of dynamics in enzyme catalysis.The Journal of chemical physics · 2016Review
- Does the pressure dependence of kinetic isotope effects report usefully on dynamics in enzyme H-transfer reactions?The FEBS journal · 2015Review
- Computer aided enzyme design and catalytic concepts.Current opinion in chemical biology · 2014Review
- Article
- Gaining insight into the chemistry of lipoxygenases: a computational investigation into the catalytic mechanism of (8R)-lipoxygenase.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2013Article
- Heavy-enzyme kinetic isotope effects on proton transfer in alanine racemase.Journal of the American Chemical Society · 2013Article
- Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis.Nature chemistry · 2012Article
- Probing quantum and dynamic effects in concerted proton-electron transfer reactions of phenol-base compounds.The journal of physical chemistry. B · 2012Article
- Examining the case for the effect of barrier compression on tunneling, vibrationally enhanced catalysis, catalytic entropy and related issues.FEBS letters · 2010Review
- At the dawn of the 21st century: Is dynamics the missing link for understanding enzyme catalysis?Proteins · 2010Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
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Registered trials
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