Evidence map›Paper›PMID 21494226›Full record

Trial reportObesity (Silver Spring, Md.)2011

Change in food cravings, food preferences, and appetite during a low-carbohydrate and low-fat diet.

Corby K Martin, Diane Rosenbaum, Hongmei Han, Paula J Geiselman, Holly R Wyatt, James O Hill, Carrie Brill, Brooke Bailer, Bernard V Miller, Rick Stein and 2 more

Open access · bronzeAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 6 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 6 syntheses or guidelines pooled it, 184 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effects of total fat intake on body fatness in adults.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Pooled it
  5. Extended calorie restriction suppresses overall and specific food cravings: a systematic review and a meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2017
    Pooled it
  6. Effects of total fat intake on body weight.The Cochrane database of systematic reviews · 2015
    Pooled it
  7. Trial
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  17. The effects of a low-carbohydrate diet on appetite: A randomized controlled trial.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
    Trial
  18. Trial
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Corby K MartinPennington Biomedical Research Center, Baton Rouge, Louisiana, USA. martinck@pbrc.edu
Diane Rosenbaum
Hongmei Han
Paula J Geiselman
Holly R Wyatt
James O Hill
Carrie Brill
Brooke Bailer
Bernard V Miller
Rick Stein
Sam Klein
Gary D Foster
Pennington Biomedical Research Center · USTemple University · USUniversity of Colorado Health · USWashington University in St. Louis · US

Funding

INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR024134 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2006 to 2011
$70.4M
ZOPOLRESTAT PHARMACOKINETICS IN DIABETICS WITH VARYING RENAL FUNCTIONM01RR000051 · NCRR · UNIVERSITY OF COLORADO DENVER · PI WALDERS, NATALIE · 1985 to 2008
$52.6M
Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Jonathan R Brestoff · 1999 to 2026
$30.2M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI ROBERT A KESTERSON · 2005 to 2026
$26.5M
The Safety and Efficacy of Low and High Carbohydrate DieR01AT001103 · NCCIH · UNIVERSITY OF PENNSYLVANIA · PI FOSTER, GARY DONALD · 2002 to 2006
$4.7M
Energy Expenditure: Relation with Body Mass Over TimeK23DK068052 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI MARTIN, CORBY K · 2006 to 2009
$300k
NCATS NIH HHS UL1 TR000448NCCIH NIH HHS AT1103NCCIH NIH HHS R01 AT001103NCRR NIH HHS M01 RR000051NCRR NIH HHS UL1 RR000051NCRR NIH HHS UL1 RR024134NCRR NIH HHS UL1RR024134NCRR NIH HHS UL1 RR024992NIDDK NIH HHS DK56341NIDDK NIH HHS K23 DK068052NIDDK NIH HHS P30 DK056341NIDDK NIH HHS P30 DK072476NIDDK NIH HHS P30 DK072476-059001
6 · The paper itself

Abstract

The study objective was to evaluate the effect of prescribing a low-carbohydrate diet (LCD) and a low-fat diet (LFD) on food cravings, food preferences, and appetite. Obese adults were randomly assigned to a LCD (n = 134) or a LFD (n = 136) for 2 years. Cravings for specific types of foods (sweets, high-fats, fast-food fats, and carbohydrates/starches); preferences for high-sugar, high-carbohydrate, and low-carbohydrate/high-protein foods; and appetite were measured during the trial and evaluated during this secondary analysis of trial data. Differences between the LCD and LFD on change in outcome variables were examined with mixed linear models. Compared to the LFD, the LCD had significantly larger decreases in cravings for carbohydrates/starches and preferences for high-carbohydrate and high-sugar foods. The LCD group reported being less bothered by hunger compared to the LFD group. Compared to the LCD group, the LFD group had significantly larger decreases in cravings for high-fat foods and preference for low-carbohydrate/high-protein foods. Men had larger decreases in appetite ratings compared to women. Prescription of diets that promoted restriction of specific types of foods resulted in decreased cravings and preferences for the foods that were targeted for restriction. The results also indicate that the LCD group was less bothered by hunger compared to the LFD group and that men had larger reductions in appetite compared to women.

Indexed as

AppetiteDiet, Carbohydrate-RestrictedDiet, Fat-RestrictedFood PreferencesAdultBehavior, AddictiveDietary CarbohydratesDietary FatsDietary ProteinsFemaleHumansMaleMiddle AgedObesitySex FactorsDietary CarbohydratesDietary FatsDietary Proteins

Identifiers

PMID21494226
PMCPMC3139783
OpenAlexW2112462453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.