Trial reportCritical care medicine2011
Real-time ultrasound-guided subclavian vein cannulation versus the landmark method in critical care patients: a prospective randomized study.
Trial report in Critical care medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 106 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Long-versus Short-Axis Ultrasound Guidance for Subclavian Vein Cannulation
Comparison of Effectiveness and Safety of Two Methods for Installing Femoral Central Venous Catheters in Pediatric Intensive Care Units : Anatomical Method vs Ultrasound in Real Time.
Ultrasound-Guided Vascular Puncture and Catheterization
Who cites it
106 citing papers in PubMed, 3 syntheses or guidelines pooled it, 374 citations in OpenAlex.
- Central venous cannulation in critically ill patients: guidelines of the Polish Society of Anaesthesiology and Intensive Therapy.Anaesthesiology intensive therapy · 2026Guideline
- Central venous catheterization site choice based on anatomical landmark technique: a systematic review and meta-analysis.Journal of anesthesia · 2021Pooled it
- Ultrasound guidance versus anatomical landmarks for subclavian or femoral vein catheterization.The Cochrane database of systematic reviews · 2015Pooled it
- Improvement of central vein ultrasound-guided puncture success using a homemade needle guide-a simulation study.Critical care (London, England) · 2023Trial
- A new method for facilitating ultrasound-guided in-plane cannulation of the subclavian vein: a randomized clinical trial.Scientific reports · 2021Trial
- Effects of ipsilateral tilt position on the cross-sectional area of the subclavian vein and the clinical performance of subclavian vein catheterization: a prospective randomized trial.BMC anesthesiology · 2020Trial
- Complications in internal jugular vs subclavian ultrasound-guided central venous catheterization: a comparative randomized trial.Intensive care medicine · 2019Trial
- A randomized clinical trial of ultrasound-guided infra-clavicular cannulation of the subclavian vein in cardiac surgical patients: short-axis versus long-axis approach.Intensive care medicine · 2017Trial
- Trial
- The influence of the direction of J-tip on the placement of a subclavian catheter: real time ultrasound-guided cannulation versus landmark method, a randomized controlled trial.BMC anesthesiology · 2014Trial
- Ultrasound-guided central venous cannulation is superior to quick-look ultrasound and landmark methods among inexperienced operators: a prospective randomized study.Intensive care medicine · 2013Trial
- Comparison between marked versus unmarked introducer needle in real-time ultrasound-guided central vein cannulation: A prospective randomized study.Annals of cardiac anaesthesiaTrial
- A comparative study of safety and efficacy of ultrasound-guided infra-clavicular axillary vein cannulation versus ultrasound-guided internal jugular vein cannulation in adult cardiac surgical patients.Annals of cardiac anaesthesiaTrial
- Real-time ultrasound guidance for central venous access: a reply.Anaesthesia · 2026Article
- Positioning Statement on the Use of Point-of-Care Ultrasound in Cardiovascular Medicine - 2026.Arquivos brasileiros de cardiologia · 2026Article
- Practice guideline on the prevention and treatment of central line-associated bloodstream infection: Part 1--Diagnosis and prevention.Journal of intensive medicine · 2026Article
- Reduced Vascular Complications After Catheter Ablation Applying Sonography-Guidance and Modified Postprocedural Care.Journal of arrhythmia · 2026Article
- Real-time ultrasound-guided subclavian vein cannulation: should it be the preferred method for central venous catheterization in critically ill?Critical care (London, England) · 2025Article
- Left-sided yoffa technique: a safe and optimized approach for totally implantable venous access device (TIVAD) placement.Langenbeck's archives of surgery · 2025Article
- Seeing Artery and VEin Simultaneously in the long axis (SAVES) for ultrasound-guided infraclavicular axillary/subclavian vein cannulation: A retrospective analysis.Journal of intensive medicine · 2025Article
46 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSubclavian vein catheterization may cause various complications. We compared the real-time ultrasound-guided subclavian vein cannulation vs. the landmark method in critical care patients.
designProspective randomized study.
settingMedical intensive care unit of a tertiary medical center. PATIENTS: Four hundred sixty-three mechanically ventilated patients enrolled in a randomized controlled ISRCTN-registered trial (ISRCTN-61258470).
interventionsWe compared the ultrasound-guided subclavian vein cannulation (200 patients) vs. the landmark method (201 patients) using an infraclavicular needle insertion point in all cases. Catheterization was performed under nonemergency conditions in the intensive care unit. Randomization was performed by means of a computer-generated random-numbers table and patients were stratified with regard to age, gender, and body mass index. MEASUREMENTS AND MAIN
resultsNo significant differences in the presence of risk factors for difficult cannulation between the two groups of patients were recorded. Subclavian vein cannulation was achieved in 100% of patients in the ultrasound group as compared with 87.5% in the landmark one (p < .05). Average access time and number of attempts were significantly reduced in the ultrasound group of patients compared with the landmark group (p < .05). In the landmark group, artery puncture and hematoma occurred in 5.4% of patients, respectively, hemothorax in 4.4%, pneumothorax in 4.9%, brachial plexus injury in 2.9%, phrenic nerve injury in 1.5%, and cardiac tamponade in 0.5%, which were all increased compared with the ultrasound group (p < .05). Catheter misplacements did not differ between groups. In this study, the real-time ultrasound method was rated on a semiquantitative scale as technically difficult by the participating physicians.
conclusionsThe present data suggested that ultrasound-guided cannulation of the subclavian vein in critical care patients is superior to the landmark method and should be the method of choice in these patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.